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Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) antibody

Antigen

Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6)
Synonyms STAT6B, STAT6C, D12S1644, IL-4-STAT
Clonality Polyclonal
Host
Alternatives

Rabbit
Reactivity
Alternatives

Human
Conjugate
Alternatives Un-conjugated
Application
Alternatives Immunohistochemistry (IHC)
5 references available
Catalog no. ABIN967102
Quantity 100ug  (100ug/100ul.)  (Variants)
Price 385.00 $   Plus shipping costs $45.00
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Alternative name STAT6
Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human STAT6 around the phosphorylation site of tyrosine 641 (R-G-YP-V-P).
Specificity STAT6 (Ab-641) antibody detects endogenous levels of total STAT6 protein.

Application Details
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Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Concentration 100ug/100ul.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative 0.02% Sodium Azide
Storage Store at -20°C/1 year.
Restrictions For Research Use only

Publications
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Product Quelle, Shimoda, Thierfelder et al.: "Cloning of murine Stat6 and human Stat6, Stat proteins that are tyrosine phosphorylated in responses to IL-4 and IL-3 but are not required for mitogenesis." in: Molecular and cellular biology, Vol. 15, Issue 6, pp. 3336-43, 1995 (PubMed).

Hou, Schindler, Henzel et al.: "An interleukin-4-induced transcription factor: IL-4 Stat." in: Science (New York, N.Y.), Vol. 265, Issue 5179, pp. 1701-6, 1994 (PubMed).

Takeda, Tanaka, Shi et al.: "Essential role of Stat6 in IL-4 signalling." in: Nature, Vol. 380, Issue 6575, pp. 627-30, 1996 (PubMed).

Malabarba, Rui, Deutsch et al.: "Interleukin-13 is a potent activator of JAK3 and STAT6 in cells expressing interleukin-2 receptor-gamma and interleukin-4 receptor-alpha." in: The Biochemical journal, Vol. 319 ( Pt 3), pp. 865-72, 1996 (PubMed).

Nelms, Keegan, Zamorano et al.: "The IL-4 receptor: signaling mechanisms and biologic functions." in: Annual review of immunology, Vol. 17, pp. 701-38, 1999 (PubMed).

Alternatives
Application Details Publications Variants back to top

Alternatives for antigen "Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6)", type "Antibodies"
Hosts Rabbit (159), Mouse (33), Chicken (2)
Reactivities Human (188), Mouse (Murine) (84), Rat (Rattus) (81), Pig (Porcine) (20), Cow (Bovine) (18), Horse (Equine) (18), Dog (Canine) (3), Monkey (3)
Applications Western Blotting (WB) (129), ELISA (57), Immunofluorescence (IF) (52), Immunohistochemistry (IHC) (44), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (36), Immunoprecipitation (IP) (27), Flow Cytometry (FACS) (9), Immunocytochemistry (ICC) (9), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (9), Immunoelectron Microscopy (IEM) (3), Fluorescence Microscopy (FM) (2), Immunohistochemistry (Frozen Sections) (IHC (fro)) (2), Immunoassay (IA) (1), Immunohistochemistry (Fixed) (IHC (fx)) (1)
Conjugates PE (4), Alexa Fluor 350 (3), Alexa Fluor 488 (3), Alexa Fluor 555 (3), Alexa Fluor 647 (3), Biotin (3), Cy3 (3), Cy5 (3), Cy5.5 (3), Cy7 (3), FITC (3), Gold (3), HRP (3), PE,Cy3 (3), PE,Cy5 (3), PE,Cy5.5 (3), PE,Cy7 (3), APC (1)
Epitopes pTyr641 (39), pThr645 (30), C-Term (29), AA 808-826 (4), Tyr641 (4), AA 630-650 (3), AA 342-640 (2), AA 806-826 (2), Internal Region (2), Thr645 (2), pTyr641,Internal Region (2), AA 61-275 (1), AA 620 (1), N-Term (1), Phosphospecific (1), pThr641 (1), pTyr642 (1), phospho (1)