SLC18A2 antibody (C-Term)

Catalog No. ABIN967117

This Rabbit Polyclonal antibody specifically detects SLC18A2 in IHC. It exhibits reactivity toward Human, Rat and Mouse and has been mentioned in 4+ publications.

Quick Overview for SLC18A2 antibody (C-Term) (ABIN967117)

Target: SLC18A2 (Solute Carrier Family 18 (Vesicular Monoamine Transporter), Member 2 (SLC18A2))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC18A2 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-SLC18A2 Antibody

Binding Specificity: C-Term

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human SVMT(Synaptic vesicular amine transporter)

Application Details

Restrictions: For Research Use only

Handling

Storage: 4 °C

References for anti-SLC18A2 antibody (ABIN967117)

Thiriot, Sievert, Ruoho: "Identification of human vesicle monoamine transporter (VMAT2) lumenal cysteines that form an intramolecular disulfide bond." in: Biochemistry, Vol. 41, Issue 20, pp. 6346-53, (2002) (PubMed).

Peter, Finn, Klisak, Liu, Kojis, Heinzmann, Roghani, Sparkes, Edwards: "Chromosomal localization of the human vesicular amine transporter genes." in: Genomics, Vol. 18, Issue 3, pp. 720-3, (1994) (PubMed).

Surratt, Persico, Yang, Edgar, Bird, Hawkins, Griffin, Li, Jabs, Uhl: "A human synaptic vesicle monoamine transporter cDNA predicts posttranslational modifications, reveals chromosome 10 gene localization and identifies TaqI RFLPs." in: FEBS letters, Vol. 318, Issue 3, pp. 325-30, (1993) (PubMed).

Erickson, Eiden: "Functional identification and molecular cloning of a human brain vesicle monoamine transporter." in: Journal of neurochemistry, Vol. 61, Issue 6, pp. 2314-7, (1993) (PubMed).

Target Details for SLC18A2

Target: SLC18A2 (Solute Carrier Family 18 (Vesicular Monoamine Transporter), Member 2 (SLC18A2))

Alternative Name: SVMT

Background: SVMT(Synaptic vesicular amine transporter) is involved in the ATP-dependent vesicular transport of biogenic amine neurotransmitters. Pumps cytosolic monoamines including dopamine, norepinephrine, serotonin, and histamine into synaptic vesicles. SVMT is requisite for vesicular amine storage prior to secretion via exocytosis. SVMT belongs to the major facilitator superfamily and vesicular transporter family.