SLC18A2 antibody (N-Term)

Catalog No. ABIN2781588

Product Details anti-SLC18A2 Antibody

Target: SLC18A2 (Solute Carrier Family 18 (Vesicular Monoamine Transporter), Member 2 (SLC18A2))

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse, Cow, Dog, Pig, Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC18A2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: NATRDLTLHQ TATQHMVTNA SAVPSDCPSE DKDLLNENVQ VGLLFASKAT

Predicted Reactivity: Cow: 100%, Dog: 86%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against SLC18A2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SLC18A2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 514 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SLC18A2

Target: SLC18A2 (Solute Carrier Family 18 (Vesicular Monoamine Transporter), Member 2 (SLC18A2))

Alternative Name: SLC18A2 (SLC18A2 Products)

Synonyms: 1110037L13Rik antibody, 9330105E13 antibody, VAT2 antibody, Vmat2 antibody, MNAT antibody, VMAT-2 antibody, VMAT2 antibody, solute carrier family 18 (vesicular monoamine), member 2 antibody, solute carrier family 18 member A2 antibody, Slc18a2 antibody

Background: The vesicular monoamine transporter acts to accumulate cytosolic monoamines into synaptic vesicles, using the proton gradient maintained across the synaptic vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine.
Alias Symbols: MGC120477, MGC120478, MGC26538, SVAT, SVMT, VAT2, VMAT2
Protein Interaction Partner: PARK7, UBC, CSNK1A1, CSNK2A2, CSNK2A1,
Protein Size: 514

Molecular Weight: 56 kDa

Gene ID: 6571

NCBI Accession: NM_003054, NP_003045

UniProt: Q05940