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WNT Inhibitory Factor 1 (WIF1) antibody

Antigen

WNT Inhibitory Factor 1 (WIF1)

Synonyms WIF-1, AW107799, MGC110507, zgc:110507, WIF1, MGC139213, shf, GB10372, wif-1
Clonality Monoclonal (1G5)
Host
Alternatives

Mouse

Reactivity
Alternatives

Human

Conjugate
Alternatives Un-conjugated
Application
Alternatives Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA
2 references available
Catalog no. ABIN967258
Quantity 0.1ml  (Variants)
Price 426.25 $   Plus shipping costs $45.00
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Additional Information

Alternative name WIF1
Gene ID 11197
Immunogen Purified recombinant fragment of human WIF1 expressed in E. Coli.
Isotype IgG1
Clone 1G5
Description The protein encoded by this gene functions to inhibit WNT proteins, which are extracellular signaling molecules that play a role in embryonic development. This protein contains a WNT inhibitory factor (WIF) domain and five epidermal growth factor (EGF)-like domains, and is thought to be involved in mesoderm segmentation. This gene functions as a tumor suppressor gene, and has been found to be epigenetically silenced in various cancers.
Synonyms: WIF-1, WIF
Molecular Weight 42kDa

Application Details

Application Notes Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
Immunofluorescence: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Purification Ascitic fluid
Preservative 0.03% sodium azide.
Storage Store at 4°C, for long term storage, store at -20°C.
Research Area Stem Cells, Wnt Signaling
Restrictions For Research Use only

Publications

Product Veeck, Wild, Fuchs et al.: "Prognostic relevance of Wnt-inhibitory factor-1 (WIF1) and Dickkopf-3 (DKK3) promoter methylation in human breast cancer." in: BMC cancer, Vol. 9, pp. 217, 2009 (PubMed).

Kawakami, Hirata, Yamamura et al.: "Functional significance of Wnt inhibitory factor-1 gene in kidney cancer." in: Cancer research, Vol. 69, Issue 22, pp. 8603-10, 2009 (PubMed).

Alternatives

Alternatives for antigen "WNT Inhibitory Factor 1 (WIF1)", type "Antibodies"
Hosts Rabbit (29), Mouse (4), Rat (1)
Reactivities Human (33), Mouse (Murine) (20), Chicken (19), Cow (Bovine) (19), Dog (Canine) (19), Horse (Equine) (19), Pig (Porcine) (19), Rat (Rattus) (19)
Applications Immunofluorescence (IF) (18), Western Blotting (WB) (18), ELISA (14), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (9), Immunohistochemistry (IHC) (4), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Flow Cytometry (FACS) (1), Immunocytochemistry (ICC) (1), Immunoelectron Microscopy (IEM) (1), Immunoprecipitation (IP) (1)
Conjugates Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
Epitopes N-Term (4), C-Term (3)