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Solute Carrier Family 30 (Zinc Transporter), Member 6 (SLC30A6) (C-Term) antibody

Details for Product No. ABIN967277, Supplier: Log in to see
Antigen
  • MST103
  • MSTP103
  • ZNT6
  • 9530029F08Rik
  • ZnT6
Epitope
C-Term
15
13
9
1
1
1
1
1
1
1
1
Reactivity
Mouse (Murine), Rat (Rattus)
22
17
6
Host
Rabbit
31
2
Clonality
Polyclonal
Conjugate
Un-conjugated
2
2
2
2
2
2
Application
Immunohistochemistry (IHC)
25
21
3
1
1
1
Supplier
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Immunogen Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to very C-terminal residues of mouse Znt6 (Zinc transporter 6) protein
Alternative Name Znt6 (SLC30A6 Antibody Abstract)
Background Znt6 (Zinc transporter 6) functions Zinc-efflux transporter which allocates the cytoplasmic zinc to the trans-Golgi network (TGN) as well as the vesicular compartment. Znt6 interacts with ZNT5. Znt6 is localized in Golgi apparatus, trans-Golgi network membrane, It is a multi-pass membrane protein and is expressed in brain and liver, and to a lower extent also in lung. Znt6 seems to have lost most of the histidine residues in the loop between the fourth and fifth transmembrane regions and appears to exert transport function by forming complexes with ZNT5. Znt6 belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family and SLC30A subfamily.
Synonyms: Slc30a6 (Solute carrier family 30 member 6)
Pathways
Restrictions For Research Use only
Product cited in: Smith, Xiong, Markesbery et al.: "Altered expression of zinc transporters-4 and -6 in mild cognitive impairment, early and late Alzheimer's disease brain." in: Neuroscience, Vol. 140, Issue 3, pp. 879-88, 2006 (PubMed).

Seve, Chimienti, Devergnas et al.: "In silico identification and expression of SLC30 family genes: an expressed sequence tag data mining strategy for the characterization of zinc transporters' tissue expression." in: BMC genomics, Vol. 5, Issue 1, pp. 32, 2004 (PubMed).

Huang, Kirschke, Gitschier: "Functional characterization of a novel mammalian zinc transporter, ZnT6." in: The Journal of biological chemistry, Vol. 277, Issue 29, pp. 26389-95, 2002 (PubMed).

Background publications Daub, Olsen, Bairlein et al.: "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle." in: Molecular cell, Vol. 31, Issue 3, pp. 438-48, 2008 (PubMed).

Bechtel, Rosenfelder, Duda et al.: "The full-ORF clone resource of the German cDNA Consortium." in: BMC genomics, Vol. 8, pp. 399, 2008 (PubMed).

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