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Adaptor-Related Protein Complex 1, gamma 1 Subunit (AP1G1) (AA 642-821) antibody

Details for Product No. ABIN967934
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Antigen
Synonyms ADTG, CLAPG1, Adtg, AA409002, AU041323, AW551707, D8Ertd374e, adtg, zgc:56079, wu:fc30a11, AP1G1, ap1g1
Epitope
AA 642-821
(4), (2), (2), (1), (1), (1)
Reactivity
Mouse (Murine)
(47), (36), (34), (29), (28), (28), (24), (1), (1), (1), (1)
Host
Mouse
(41), (9), (7)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1)
Application
Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC), Immunofluorescence (IF)
(32), (20), (19), (12), (6), (6), (4), (1), (1), (1)
Pubmed 5 references available
Quantity 50 µg
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Catalog No. ABIN967934
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Immunogen Mouse Adaptin gamma
Clone MOC-1
Isotype IgG1
Cross-Reactivity Rat (Rattus), Human, Dog (Canine)
Characteristics 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
Purification Purified from tissue culture supernatant or ascites by affinity chromatography.
Purity Purified
Alternative Name Adaptin gamma
Background Sorting of integral membrane proteins at various stages of the endocytic and secretory pathways is mediated by vesicular trafficking between a variety of organelles. Two sorting signals are tyrosine-based and dileucine-based signals that interact with heterotetrameric adaptor protein complexes (AP-1, AP-2, AP-3, and AP-4), which are associated with the vesicle coats. These coatomers contain two large Adaptin proteins (gamma, alpha, delta, or epsilon and beta1, beta2, beta3, or beta4, respectively) that are noncovalently linked to one medium chain (µ1, µ2, µ3, or µ4) and one small chain ( sigma1, sigma2, sigma3, or sigma4). The AP-1 and AP-3 complexes are involved in protein sorting from the TGN and endosomes, while AP-2 adaptor complexes are involved in clathrin-mediated endocytosis. Adaptin gamma shows more homology with Adaptin alpha than with Adaptin beta. The conserved regions between Adaptins gamma and alpha could be important for binding to other components of the AP-1 and AP-2 complexes, respectively.
Molecular Weight 104 kDa
Comment

Related Products: ABIN968539, ABIN967389

Restrictions For Research Use only
Format Liquid
Concentration 250 µg/ml
Buffer Aqueous buffered solution containing BSA, glycerol.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Supplier Images
anti-Adaptor-Related Protein Complex 1, gamma 1 Subunit (AP1G1) (AA 642-821) antibody Western blot analysis of Adaptin gamma on PC12 cell lysate. Lane 1: 1:5000, lane 2: 1:10000, lane 3: 1:20000 dilution of anti-Adaptin gamma.
anti-Adaptor-Related Protein Complex 1, gamma 1 Subunit (AP1G1) (AA 642-821) antibody (2) Immunofluorescent staining of Rat Neurons with anti-Adaptin gamma antibody.
Product cited in: Robinson: "Cloning and expression of gamma-adaptin, a component of clathrin-coated vesicles associated with the Golgi apparatus." in: The Journal of cell biology, Vol. 111, Issue 6 Pt 1, pp. 2319-26, 1991 (PubMed).

Wasiak, Legendre-Guillemin, Puertollano et al.: "Enthoprotin: a novel clathrin-associated protein identified through subcellular proteomics." in: The Journal of cell biology, Vol. 158, Issue 5, pp. 855-62, 2002 (PubMed).

Eskelinen, Illert, Tanaka et al.: "Role of LAMP-2 in lysosome biogenesis and autophagy." in: Molecular biology of the cell, Vol. 13, Issue 9, pp. 3355-68, 2002 (PubMed).

Kalthoff, Groos, Kohl et al.: "Clint: a novel clathrin-binding ENTH-domain protein at the Golgi." in: Molecular biology of the cell, Vol. 13, Issue 11, pp. 4060-73, 2002 (PubMed).

Nagahama, Suzuki, Hamada et al.: "SVIP is a novel VCP/p97-interacting protein whose expression causes cell vacuolation." in: Molecular biology of the cell, Vol. 14, Issue 1, pp. 262-73, 2003 (PubMed).

Hosts (41), (9), (7)
Reactivities (47), (36), (34), (29), (28), (28), (24), (1), (1), (1), (1)
Applications (32), (20), (19), (12), (6), (6), (4), (1), (1), (1)
Conjugates (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1)
Epitopes (4), (2), (2), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN967934
Contact our Customer Service for availability and price in your country.
Add to Basket

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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