gamma 1 Adaptin antibody (C-Term)

Catalog No. ABIN2784689

The Rabbit Polyclonal anti-gamma 1 Adaptin antibody (ABIN2784689) specifically detects gamma 1 Adaptin in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Horse, Pig and Rabbit samples.

Quick Overview for gamma 1 Adaptin antibody (C-Term) (ABIN2784689)

Target: gamma 1 Adaptin (AP1G1) (Adaptor-Related Protein Complex 1, gamma 1 Subunit (AP1G1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This gamma 1 Adaptin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-gamma 1 Adaptin Antibody

Binding Specificity: C-Term

Purpose: AP1G1 Antibody - C-terminal region

Sequence: DHMRSALLER MPVMEKVTTN GPTEIVQTNG ETEPAPLETK PPPSGPQPTS

Predicted Reactivity: Cow: 86%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against AP1G1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human AP1G1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP51923-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for gamma 1 Adaptin

Target: gamma 1 Adaptin (AP1G1) (Adaptor-Related Protein Complex 1, gamma 1 Subunit (AP1G1))

Alternative Name: AP1G1

Background:

Targeted Subunit: gamma-1

Background Information: Adaptins are important components of clathrin-coated vesicles transporting ligand-receptor complexes from the plasma membrane or from the trans-Golgi network to lysosomes. The adaptin family of proteins is composed of four classes of molecules named alpha, beta-, beta prime- and gamma- adaptins. Adaptins, together with medium and small subunits, form a heterotetrameric complex called an adaptor, whose role is to promote the formation of clathrin-coated pits and vesicles. AP1G1 is a gamma-adaptin protein and it belongs to the adaptor complexes large subunits family.Adaptins are important components of clathrin-coated vesicles transporting ligand-receptor complexes from the plasma membrane or from the trans-Golgi network to lysosomes. The adaptin family of proteins is composed of four classes of molecules named alpha, beta-, beta prime- and gamma- adaptins. Adaptins, together with medium and small subunits, form a heterotetrameric complex called an adaptor, whose role is to promote the formation of clathrin-coated pits and vesicles. The protein encoded by this gene is a gamma-adaptin protein and it belongs to the adaptor complexes large subunits family. Two transcript variants encoding different isoforms have been found for this gene.

Gene Name: Adaptor-related protein complex 1, gamma 1 subunit

Alternative Symbols: ADTG, CLAPG1

Protein Name: AP-1 complex subunit gamma-1

Molecular Weight: 91kDa

Gene ID: 164

NCBI Accession: NP_001119

UniProt: O43747