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AXL Receptor tyrosine Kinase (AXL) (AA 466-530) antibody

Antigen

AXL Receptor tyrosine Kinase (AXL)
Binding Site
Alternatives

AA 466-530
Clonality Monoclonal (1B3A2)
Host
Alternatives

Mouse
Reactivity
Alternatives

Human
Conjugate
Alternatives Un-conjugated
Application
Alternatives ELISA, Western Blotting (WB)
2 references available
Catalog no. ABIN968973
Quantity 0.1ml  (Variants)
Price 297.00 $   Plus shipping costs $45.00
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Additional Information
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Alternative name AXL
Gene ID 558
Immunogen Purified recombinant fragment of AXL(AA 466-530) expressed in E. Coli.
Format Liquid
Isotype IgG1
Clone 1B3A2
Description AXL: AXL receptor tyrosine kinase. The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified.
Synonyms: UFO, JTK11

Application Details
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Application Notes Western Blotting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Purification Ascites
Buffer Ascitic fluid containing 0.03% sodium azide.
Preservative 0.03% sodium azide
Storage Store at 4℃, for long term storage, store at -20℃.
Restrictions For Research Use only

Publications
Application Details Alternatives Variants back to top

Product Rual, Venkatesan, Hao et al.: "Towards a proteome-scale map of the human protein-protein interaction network." in: Nature, Vol. 437, Issue 7062, pp. 1173-8, 2005 (PubMed).

Budagian, Bulanova, Orinska et al.: "Soluble Axl is generated by ADAM10-dependent cleavage and associates with Gas6 in mouse serum." in: Molecular and cellular biology, Vol. 25, Issue 21, pp. 9324-39, 2005 (PubMed).

Alternatives
Application Details Publications Variants back to top

Alternatives for antigen "AXL Receptor tyrosine Kinase (AXL)", type "Antibodies"
Hosts Rabbit (52), Mouse (12), Goat (2), Rat (1)
Reactivities Human (67), Mouse (Murine) (33), Rat (Rattus) (32), Cow (Bovine) (24), Dog (Canine) (24), Horse (Equine) (23), Pig (Porcine) (23), Cat (Feline) (1), Chicken (1), Monkey (1)
Applications Western Blotting (WB) (43), ELISA (34), Immunofluorescence (IF) (27), Flow Cytometry (FACS) (18), Immunohistochemistry (IHC) (11), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (8), Immunocytochemistry (ICC) (4), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunoprecipitation (IP) (2), Immunoelectron Microscopy (IEM) (1)
Conjugates Alexa Fluor 350 (2), Alexa Fluor 488 (2), Alexa Fluor 555 (2), Alexa Fluor 647 (2), PE,Cy5.5 (2), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy7 (1)
Epitopes C-Term (5), pTyr703,pTyr702,pTyr698 (4), N-Term (3), AA 195-212 (1), AA 450-500 (1), AA 466-530 (1), AA 514-527 (1), AA 785-801 (1), C-Term,pTyr698,pTyr702,pTyr703 (1), Extracellular (1), Extracellular Domain (1), Tyr779 (1), pTyr691 (1), pTyr779 (1), pTyr798 (1)