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Details for Product No. ABIN968973

AXL Receptor tyrosine Kinase (AXL) (AA 466-530) antibody

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Antigen
Synonyms Ark, Ufo, Tyro7, AI323647, UFO, JTK11
Epitope
»Alternatives AA 466-530
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives ELISA, Western Blotting (WB)
Pubmed 2 references available
Catalog no. ABIN968973
Quantity 100 µL
Price
297.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 3 to 4 Business Days
Immunogen Purified recombinant fragment of AXL (AA 466-530) expressed in E. coli.
Clone 1B3A2
Isotype IgG1
Purification Ascites
Alternative Name AXL
Background Synonyms:
UFO, JTK11
AXL: AXL receptor tyrosine kinase. The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified.
Gene ID 558
Application Notes Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.
Product cited in: Rual, Venkatesan, Hao et al.: "Towards a proteome-scale map of the human protein-protein interaction network." in: Nature, Vol. 437, Issue 7062, pp. 1173-8, 2005 (PubMed).

Budagian, Bulanova, Orinska et al.: "Soluble Axl is generated by ADAM10-dependent cleavage and associates with Gas6 in mouse serum." in: Molecular and cellular biology, Vol. 25, Issue 21, pp. 9324-39, 2005 (PubMed).

Alternatives for antigen "AXL Receptor tyrosine Kinase (AXL)", type "Antibodies"
Hosts (78), (26), (4), (1)
Reactivities (105), (48), (45), (34), (19), (17), (1)
Applications (77), (45), (37), (20), (16), (14), (9), (6), (2), (2), (1), (1)
Conjugates (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Epitopes (18), (18), (18), (9), (8), (5), (4), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
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