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AXL antibody

AXL Reactivity: Human WB, ELISA, ICC Host: Mouse Monoclonal 7-00E-10 unconjugated
Catalog No. ABIN968974
  • Target See all AXL Antibodies
    AXL (AXL Receptor tyrosine Kinase (AXL))
    Reactivity
    • 136
    • 62
    • 55
    • 6
    • 5
    • 5
    • 5
    • 2
    • 1
    • 1
    Human
    Host
    • 124
    • 18
    • 3
    • 1
    Mouse
    Clonality
    • 124
    • 22
    Monoclonal
    Conjugate
    • 59
    • 12
    • 11
    • 10
    • 8
    • 8
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This AXL antibody is un-conjugated
    Application
    • 117
    • 69
    • 38
    • 26
    • 26
    • 21
    • 15
    • 9
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
    Purification
    purified
    Immunogen
    Purified recombinant extracellular fragment of human AXL fused with hIgGFc tag expressed in HEK293 cell line.
    Clone
    7-00E-10
    Isotype
    IgG1
    Top Product
    Discover our top product AXL Primary Antibody
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Vajkoczy, Knyazev, Kunkel, Capelle, Behrndt, von Tengg-Kobligk, Kiessling, Eichelsbacher, Essig, Read, Erber, Ullrich: "Dominant-negative inhibition of the Axl receptor tyrosine kinase suppresses brain tumor cell growth and invasion and prolongs survival." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 15, pp. 5799-804, (2006) (PubMed).

  • Target
    AXL (AXL Receptor tyrosine Kinase (AXL))
    Alternative Name
    AXL (AXL Products)
    Synonyms
    JTK11 antibody, UFO antibody, AI323647 antibody, Ark antibody, Tyro7 antibody, Ufo antibody, AXL receptor tyrosine kinase antibody, Axl receptor tyrosine kinase antibody, AXL antibody, Axl antibody
    Background

    Description: AXL: AXL receptor tyrosine kinase, also known as UFO, JTK11. Entrez Protein NP_001690. It is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified.

    Aliases: UFO, JTK11

    Molecular Weight
    97.4 kDa
    Gene ID
    558
    HGNC
    558
    Pathways
    RTK Signaling, Cellular Response to Molecule of Bacterial Origin
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