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V-Rel Reticuloendotheliosis Viral Oncogene Homolog (Avian) (REL) antibody

Antigen

V-Rel Reticuloendotheliosis Viral Oncogene Homolog (Avian) (REL)
Synonyms C-Rel, rel-A, Xrel2, REL
Clonality Monoclonal (1E7)
Host
Alternatives

Mouse
Reactivity
Alternatives

Human, Mouse (Murine)
Conjugate
Alternatives Un-conjugated
Application
Alternatives ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
2 references available
Catalog no. ABIN968997
Quantity 0.1ml  (Variants)
Price 396.00 $   Plus shipping costs $45.00
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Additional Information
Application Details Publications Alternatives Variants back to top

Alternative name c-Rel
Gene ID 6606
Immunogen Purified recombinant fragment of human c-Rel expressed in E. Coli.
Format Liquid
Isotype IgG1
Clone 1E7
Description The REL gene encodes c-Rel, a transcription factor that is a member of the Rel/NFKB family, which also includes RELA (MIM 164014), RELB (604758), NFKB1 (MIM 164011), and NFKB2 (MIM 164012). These proteins are related through a highly conserved N-terminal region termed the 'Rel domain,' which is responsible for DNA binding, dimerization, nuclear localization, and binding to the NFKB inhibitor.
Synonyms: Rel, c-Rel
Molecular Weight 78kDa

Application Details
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Application Notes Western Blotting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
Immunofluorescence: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Purification Ascites
Buffer Ascitic fluid containing 0.03% sodium azide.
Preservative 0.03% sodium azide
Storage Store at 4℃, for long term storage, store at -20℃.
Research Area Cancer, Transcription Factors
Restrictions For Research Use only

Publications
Application Details Alternatives Variants back to top

Product Garbati, Gilmore: "Ser484 and Ser494 in REL are the major sites of IKK phosphorylation in vitro: evidence that IKK does not directly enhance GAL4-REL transactivation." in: Gene expression, Vol. 14, Issue 4, pp. 195-205, 2008 (PubMed).

Trynka, Zhernakova, Romanos et al.: "Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling." in: Gut, Vol. 58, Issue 8, pp. 1078-83, 2009 (PubMed).

Alternatives
Application Details Publications Variants back to top

Alternatives for antigen "V-Rel Reticuloendotheliosis Viral Oncogene Homolog (Avian) (REL)", type "Antibodies"
Hosts Rabbit (62), Goat (3), Mouse (3)
Reactivities Human (65), Mouse (Murine) (24), Chicken (19), Horse (Equine) (18), Pig (Porcine) (18), Rat (Rattus) (18), Dog (Canine) (1), Xenopus laevis (1), Zebrafish (1)
Applications Western Blotting (WB) (39), ELISA (30), Immunofluorescence (IF) (29), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (7), Immunoprecipitation (IP) (7), Immunohistochemistry (IHC) (6), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Gel Shift (GS) (2), Immunocytochemistry (ICC) (2), Electrophoretic Mobility-Shift Assay (EMSA) (1), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (Fixed) (IHC (fx)) (1)
Conjugates Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
Epitopes C-Term (8), pSer503 (7), Internal Region (4), Ser503 (2), AA 10-28 (1), AA 276-291 (1), Center (1), N-Term (1)