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Details for Product No. ABIN969010

Chaperonin Containing TCP1, Subunit 2 (Beta) (CCT2) antibody

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Antigen
Synonyms 99D8.1, CCT-beta, CCTB, PRO1633, TCP-1-beta, Cctb, fa26a01, fc58a11, CHUNP6883, wu:fa26a01, wu:fc58a11, cct2, MGC89448, CCT2
Reactivity
»Alternatives Human, Mouse (Murine), Monkey, Rat (Rattus)
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives ELISA, Western Blotting (WB), Immunocytochemistry (ICC), Fluorescence Microscopy (FM)
Pubmed 2 references available
Catalog no. ABIN969010
Quantity 100 µL
Price
396.00 $   Plus shipping costs $45.00
Shipping to
Availability Will be delivered in 3 to 4 Business Days
Immunogen Purified recombinant fragment of human CCT2 expressed in E. coli.
Clone 5B5C4
Isotype IgG1
Purification Ascites
Alternative Name CCT2
Background Synonyms:
CCTB, 99D8. 1, PRO1633, CCT-β, MGC142074, MGC142076, TCP-1-β
The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Two transcript variants encoding different isoforms have been found for this gene.
Molecular Weight 54 kDa
Gene ID 10576
Application Notes Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000, ICC: 1/200 - 1/1000, FCM: 1/200 - 1/400
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.
Product cited in: Goudreault, DAmbrosio, Kean et al.: "A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein." in: Molecular & cellular proteomics : MCP, Vol. 8, Issue 1, pp. 157-71, 2009 (PubMed).

Abe, Yoon, Kubota et al.: "p90 ribosomal S6 kinase and p70 ribosomal S6 kinase link phosphorylation of the eukaryotic chaperonin containing TCP-1 to growth factor, insulin, and nutrient signaling." in: The Journal of biological chemistry, Vol. 284, Issue 22, pp. 14939-48, 2009 (PubMed).

Alternatives for antigen "Chaperonin Containing TCP1, Subunit 2 (Beta) (CCT2)", type "Antibodies"
Hosts (23), (17), (9)
Reactivities (43), (23), (22), (15), (15), (14), (14), (4), (3), (3), (3), (2), (1), (1)
Applications (39), (14), (11), (10), (4), (3), (3), (3), (2), (2)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (13), (2), (2), (1), (1), (1)
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