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CD33 Molecule (CD33) (AA 48-258) antibody

Antigen

CD33 Molecule (CD33)
Synonyms CD33, p67, SIGLEC3, FLJ00391, SIGLEC-3
Binding Site
Alternatives

AA 48-258
Clonality Monoclonal (2B7C12)
Host
Alternatives

Mouse
Reactivity
Alternatives

Human
Conjugate
Alternatives Un-conjugated
Application
Alternatives ELISA, Western Blotting (WB)
2 references available
Catalog no. ABIN969020
Quantity 0.1ml
Price 407.00 $   Plus shipping costs $45.00
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Additional Information
Application Details Publications Alternatives back to top

Alternative name CD33
Gene ID 945
Immunogen Purified recombinant fragment of CD33 (48-258) expressed in E. Coli.
Format Liquid
Isotype IgG1
Clone 2B7C12
Description CD33 is found on granulocyte and macrophage precursors in the bone marrow, but is not on pluripotent stem cells. The protein is also expressed on, and is a useful marker for, peripheral monocytes. It is also useful for distinguishing myelogenous leukaemia cells from lymphoid or erythroid leukaemias.
Synonyms: p67, SIGLEC3

Application Details
Publications Alternatives back to top

Application Notes Western Blotting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Purification Ascites
Buffer Ascitic fluid containing 0.03% sodium azide.
Preservative 0.03% sodium azide
Storage Store at 4℃, for long term storage, store at -20℃.
Research Area Stem Cells, Hematopoietic Progenitors, Hematopoietic Stem Cells, CD Antigens, Surface Receptors of Immune Cells
Restrictions For Research Use only

Publications
Application Details Alternatives back to top

Product Balaian, Ball: "Anti-CD33 monoclonal antibodies enhance the cytotoxic effects of cytosine arabinoside and idarubicin on acute myeloid leukemia cells through similarities in their signaling pathways." in: Experimental hematology, Vol. 33, Issue 2, pp. 199-211, 2005 (PubMed).

Plesa, Chelghoum, Plesa et al.: "Prognostic value of immunophenotyping in elderly patients with acute myeloid leukemia: a single-institution experience." in: Cancer, Vol. 112, Issue 3, pp. 572-80, 2008 (PubMed).

Alternatives
Application Details Publications back to top

Alternatives for antigen "CD33 Molecule (CD33)", type "Antibodies"
Hosts Mouse (139), Rabbit (66)
Reactivities Human (185), Mouse (Murine) (39), Rat (Rattus) (39), Primate (28), Cat (Feline) (1), Chicken (1), Cow (Bovine) (1), Dog (Canine) (1)
Applications Flow Cytometry (FACS) (141), Immunofluorescence (IF) (51), Western Blotting (WB) (50), Immunoprecipitation (IP) (30), ELISA (22), Immunohistochemistry (Frozen Sections) (IHC (fro)) (20), Functional Studies (Func) (17), Immunocytochemistry (ICC) (14), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (13), Immunohistochemistry (Fixed) (IHC (fx)) (12), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (9), Immunohistochemistry (IHC) (6), Immunoelectron Microscopy (IEM) (3)
Conjugates PE (27), FITC (22), Biotin (14), APC (10), Cy5,PE (6), Cy5.5 (5), Cy5 (4), PE-Cy5 (4), RPE (4), Alexa Fluor 350 (3), Alexa Fluor 555 (3), Alexa Fluor 647 (3), Cy3 (3), Cy7 (3), Gold (3), HRP (3), PE-Cy5.5 (3), PerCP (3), Alexa Fluor 700 (2), Cy7,PE (2), PE,Cy3 (2), PE,Cy5 (2), PE,Cy7 (2), PE-Dyomics 647 (2), Alexa Fluor 488 (1), CF (1), PE,Cy5.5 (1), PE-Cy3 (1), PE-Cy7 (1), PerCP-Cy5.5 (1), RPE,Cy5 (1), SPRD (1)
Epitopes C-Term (8), N-Term (4), Center (1), Internal Region (1), Middle Region (1)