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Details for Product No. ABIN969042

Cyclin-Dependent Kinase 9 (CDK9) antibody

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Antigen
Synonyms TAK, C-2k, CTK1, CDC2L4, PITALRE, wu:fb22e09, wu:fc06c02, CDK9, CG5179, Dmel\\CG5179, P-TEF, P-TEFb, PTefb, cdk9, c-2k, cdc2l4, ctk1, pitalre, tak
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 2 references available
Catalog no. ABIN969042
Quantity 100 µL
Price
396.00 $   Plus shipping costs $45.00
Shipping to
Availability Will be delivered in 3 to 4 Business Days
Immunogen Purified recombinant fragment of human CDK9 expressed in E. coli.
Clone 1B5A7
Isotype IgG1
Purification Ascites
Alternative Name CDK9
Background Synonyms:
TAK, C-2k, CTK1, CDC2L4, PITALRE
The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS. (provided by RefSeq) Tissue specificity: Ubiquitous.
Molecular Weight 43 kDa
Gene ID 1025
Research Area Cell Cycle
Application Notes Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.
Product cited in: Montanuy, Torremocha, Hernández-Munain et al.: "Promoter influences transcription elongation: TATA-box element mediates the assembly of processive transcription complexes responsive to cyclin-dependent kinase 9." in: The Journal of biological chemistry, Vol. 283, Issue 12, pp. 7368-78, 2008 (PubMed).

Sabò, Lusic, Cereseto et al.: "Acetylation of conserved lysines in the catalytic core of cyclin-dependent kinase 9 inhibits kinase activity and regulates transcription." in: Molecular and cellular biology, Vol. 28, Issue 7, pp. 2201-12, 2008 (PubMed).

Alternatives for antigen "Cyclin-Dependent Kinase 9 (CDK9)", type "Antibodies"
Hosts (75), (20)
Reactivities (93), (50), (46), (33), (33), (33), (25), (8), (1), (1)
Applications (70), (49), (26), (25), (19), (16), (5), (3), (3), (3), (3), (2), (2), (1), (1)
Conjugates (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2)
Epitopes (18), (16), (9), (7), (2), (2), (1), (1)
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