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Details for Product No. ABIN969159

FYN Oncogene Related To SRC, FGR, YES (FYN) antibody

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Antigen
Synonyms fyn, c-fyn, zgc:86720, SLK, SYN, p59-FYN, AI448320, AW552119, PKC, cfyn-a, im:6908851, si:dkey-119m7.5, zgc:109996
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Fluorescence Microscopy (FM)
Pubmed 3 references available
Catalog no. ABIN969159
Quantity 100 µL
Price
396.00 $   Plus shipping costs $45.00
Shipping to
Availability Will be delivered in 3 to 4 Business Days
Immunogen Purified recombinant fragment of human FYN expressed in E. coli.
Clone 2A10
Isotype IgG1
Purification Ascites
Alternative Name FYN
Background Synonyms:
SLK, SYN, MGC45350
This gene is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein. Alternatively spliced transcript variants encoding distinct isoforms exist.
Molecular Weight 61 kDa
Gene ID 2534
Application Notes Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, ICC: 1/200 - 1/1000, FCM: 1/200 - 1/400
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.
Product cited in: Kitkumthorn, Yanatatsanajit, Kiatpongsan et al.: "Cyclin A1 promoter hypermethylation in human papillomavirus-associated cervical cancer." in: BMC cancer, Vol. 6, pp. 55, 2006 (PubMed).

Lu, Zhu, Cvrljevic et al.: "Fyn and SRC are effectors of oncogenic epidermal growth factor receptor signaling in glioblastoma patients." in: Cancer research, Vol. 69, Issue 17, pp. 6889-98, 2009 (PubMed).

Brignatz, Paronetto, Opi et al.: "Alternative splicing modulates autoinhibition and SH3 accessibility in the Src kinase Fyn." in: Molecular and cellular biology, Vol. 29, Issue 24, pp. 6438-48, 2009 (PubMed).

Alternatives for antigen "FYN Oncogene Related To SRC, FGR, YES (FYN)", type "Antibodies"
Hosts (79), (50), (10)
Reactivities (124), (84), (49), (28), (27), (27), (25), (2)
Applications (110), (58), (34), (23), (20), (16), (12), (11), (9), (6), (4), (3), (3), (2), (2), (2)
Conjugates (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Epitopes (21), (17), (7), (7), (5), (4), (4), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
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