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FYN antibody (FYN Oncogene Related To SRC, FGR, YES)

Details for Product anti-FYN Antibody No. ABIN969159, Supplier: Login to see New
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Synonyms im:6908851, si:dkey-119m7.5, zgc:109996, c-fyn, cfyn-a, SLK, SYN, p59-FYN, PKC, fyn, zgc:86720, AI448320, AW552119
(179), (87), (35), (7), (7), (7), (2), (1), (1), (1), (1), (1)
(131), (61), (11)
Clonality (Clone)
Monoclonal ()
This FYN antibody is un-conjugated
(6), (6), (6), (6), (6), (6)
Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
(182), (104), (46), (25), (22), (17), (13), (13), (6), (4), (2), (2), (2), (1)
Pubmed 3 references available
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Quantity 100 μL
Shipping to United States ( )
Availability Will be delivered in 3 to 4 Business Days
Immunogen Purified recombinant fragment of human FYN expressed in E. coli.
Clone 2A10
Isotype IgG1
Purification Ascites
Alternative Name FYN (FYN Antibody Abstract)
Background This gene is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein. Alternatively spliced transcript variants encoding distinct isoforms exist.
Molecular Weight 61 kDa
Gene ID 2534
HGNC 2534
Pathways JAK-STAT Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Application Notes Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, ICC: 1/200 - 1/1000, FCM: 1/200 - 1/400
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.
Supplier Images
ELISA image for anti-FYN antibody (FYN Oncogene Related To SRC, FGR, YES) (ABIN969159) Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 n...
Flow Cytometry (FACS) image for anti-FYN antibody (FYN Oncogene Related To SRC, FGR, YES) (ABIN969159) Figure 2: Flow cytometric analysis of Hela cells using FYN mouse mAb (green) and nega...
Immunocytochemistry (ICC) image for anti-FYN antibody (FYN Oncogene Related To SRC, FGR, YES) (ABIN969159) Figure 3: Immunofluorescence analysis of U251 cells using FYN mouse mAb (green) . Blu...
Immunohistochemistry (IHC) image for anti-FYN antibody (FYN Oncogene Related To SRC, FGR, YES) (ABIN969159) Figure 4: Immunohistochemical analysis of paraffin-embedded breast cancer tissues (le...
Western Blotting (WB) image for anti-FYN antibody (FYN Oncogene Related To SRC, FGR, YES) (ABIN969159) Figure 5: Western blot analysis using FYN mAb against human FYN (AA: 7-176) recombina...
Product cited in: Brignatz, Paronetto, Opi et al.: "Alternative splicing modulates autoinhibition and SH3 accessibility in the Src kinase Fyn." in: Molecular and cellular biology, Vol. 29, Issue 24, pp. 6438-48, 2009 (PubMed).

Lu, Zhu, Cvrljevic et al.: "Fyn and SRC are effectors of oncogenic epidermal growth factor receptor signaling in glioblastoma patients." in: Cancer research, Vol. 69, Issue 17, pp. 6889-98, 2009 (PubMed).

Kitkumthorn, Yanatatsanajit, Kiatpongsan et al.: "Cyclin A1 promoter hypermethylation in human papillomavirus-associated cervical cancer." in: BMC cancer, Vol. 6, pp. 55, 2006 (PubMed).

Catalog No. ABIN969159
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