anti-FYN antibody (FYN Oncogene Related To SRC, FGR, YES)

Details for Product anti-FYN Antibody No. ABIN969159
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Antigen
Synonyms im:6908851, si:dkey-119m7.5, zgc:109996, c-fyn, cfyn-a, SLK, SYN, p59-FYN, PKC, fyn, zgc:86720, AI448320, AW552119
Reactivity
Human
(186), (95), (39), (5), (5), (5), (1), (1), (1), (1), (1)
Host
Mouse
(129), (60), (21)
Clonality (Clone)
Monoclonal ()
Conjugate
This FYN antibody is un-conjugated
(8), (7), (7), (7), (7), (7)
Application
ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (IHC), Western Blotting (WB)
(190), (113), (44), (25), (19), (12), (11), (11), (9), (6), (4), (2), (2), (2), (2), (2), (1)
Pubmed 3 references available
Quantity 100 μL
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Immunogen Purified recombinant fragment of human FYN expressed in E. coli.
Clone 2A10
Isotype IgG1
Purification Ascites
Alternative Name FYN (FYN Antibody Abstract)
Background This gene is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein. Alternatively spliced transcript variants encoding distinct isoforms exist.
Molecular Weight 61 kDa
Gene ID 2534
HGNC 2534
Pathways JAK/ STAT Signaling
Application Notes Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, ICC: 1/200 - 1/1000, FCM: 1/200 - 1/400
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.
Supplier Images
anti-FYN Oncogene Related To SRC, FGR, YES (FYN) antibody Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 ng), Blue: ...
anti-FYN Oncogene Related To SRC, FGR, YES (FYN) antibody (2) Figure 3: Flow cytometric analysis of Hela cells using FYN mouse mAb (green) and nega...
anti-FYN Oncogene Related To SRC, FGR, YES (FYN) antibody (3) Figure 3: Immunofluorescence analysis of U251 cells using FYN mouse mAb (green) . Blu...
anti-FYN Oncogene Related To SRC, FGR, YES (FYN) antibody (4) Figure 2: Immunohistochemical analysis of paraffin-embedded breast cancer tissues (le...
anti-FYN Oncogene Related To SRC, FGR, YES (FYN) antibody (5) Figure 1: Western blot analysis using FYN mAb against human FYN (AA: 7-176) recombina...
Product cited in: Brignatz, Paronetto, Opi et al.: "Alternative splicing modulates autoinhibition and SH3 accessibility in the Src kinase Fyn." in: Molecular and cellular biology, Vol. 29, Issue 24, pp. 6438-48, 2009 (PubMed).

Lu, Zhu, Cvrljevic et al.: "Fyn and SRC are effectors of oncogenic epidermal growth factor receptor signaling in glioblastoma patients." in: Cancer research, Vol. 69, Issue 17, pp. 6889-98, 2009 (PubMed).

Kitkumthorn, Yanatatsanajit, Kiatpongsan et al.: "Cyclin A1 promoter hypermethylation in human papillomavirus-associated cervical cancer." in: BMC cancer, Vol. 6, pp. 55, 2006 (PubMed).

Validation Images
Catalog No. ABIN969159
430.10 $
Plus shipping costs $45.00
Quantity
Price
100 μL
430.10 $

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