FYN Oncogene Related To SRC, FGR, YES (FYN) antibody

Details for Product No. ABIN969159
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms im:6908851, si:dkey-119m7.5, zgc:109996, c-fyn, cfyn-a, SLK, SYN, p59-FYN, PKC, fyn, zgc:86720, AI448320, AW552119
Reactivity
Human
(158), (100), (61), (27), (27), (27), (25), (1)
Host
Mouse
(118), (47), (9)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(6), (5), (5), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2)
Application
ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Fluorescence Microscopy (FM)
(145), (83), (31), (31), (20), (14), (12), (12), (11), (6), (3), (2), (2)
Pubmed 3 references available
Quantity 100 µL
Options
Shipping to United States (Change)
Availability Will be delivered in 3 to 4 Business Days
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN969159
396.00 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Purified recombinant fragment of human FYN expressed in E. coli.
Clone 2A10
Isotype IgG1
Purification Ascites
Alternative Name FYN
Background Synonyms:
SLK, SYN, MGC45350
This gene is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein. Alternatively spliced transcript variants encoding distinct isoforms exist.
Molecular Weight 61 kDa
Gene ID 2534
Application Notes Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, ICC: 1/200 - 1/1000, FCM: 1/200 - 1/400
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.
Supplier Images
anti-FYN Oncogene Related To SRC, FGR, YES (FYN) antibody Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 ng), Blue: Antigen (100 ng)
anti-FYN Oncogene Related To SRC, FGR, YES (FYN) antibody (2) Figure 3: Flow cytometric analysis of Hela cells using FYN mouse mAb (green) and negative control (purple) .
anti-FYN Oncogene Related To SRC, FGR, YES (FYN) antibody (3) Figure 3: Immunofluorescence analysis of U251 cells using FYN mouse mAb (green) . Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
anti-FYN Oncogene Related To SRC, FGR, YES (FYN) antibody (4) Figure 2: Immunohistochemical analysis of paraffin-embedded breast cancer tissues (left) and brain tissues (right) using FYN mouse mAb with DAB staining.
anti-FYN Oncogene Related To SRC, FGR, YES (FYN) antibody (5) Figure 1: Western blot analysis using FYN mAb against human FYN (AA: 7-176) recombinant protein. (Expected MW is 44.3 kDa)
Product cited in: Kitkumthorn, Yanatatsanajit, Kiatpongsan et al.: "Cyclin A1 promoter hypermethylation in human papillomavirus-associated cervical cancer." in: BMC cancer, Vol. 6, pp. 55, 2006 (PubMed).

Lu, Zhu, Cvrljevic et al.: "Fyn and SRC are effectors of oncogenic epidermal growth factor receptor signaling in glioblastoma patients." in: Cancer research, Vol. 69, Issue 17, pp. 6889-98, 2009 (PubMed).

Brignatz, Paronetto, Opi et al.: "Alternative splicing modulates autoinhibition and SH3 accessibility in the Src kinase Fyn." in: Molecular and cellular biology, Vol. 29, Issue 24, pp. 6438-48, 2009 (PubMed).

Validation Images
Did you look for something else?
back to top