GABPA antibody (AA 120-190)

Catalog No. ABIN969163

This Mouse Monoclonal antibody specifically detects GABPA in WB, ELISA and ICC. It exhibits reactivity toward Human and Mouse and has been mentioned in 2+ publications.

Quick Overview for GABPA antibody (AA 120-190) (ABIN969163)

Target: GABPA (GA Binding Protein Transcription Factor, alpha Subunit 60kDa (GABPA))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This GABPA antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Clone: 8C1B10

Product Details anti-GABPA Antibody

Binding Specificity: AA 120-190

Purpose: GABPA Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human GABPA (aa120-190) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-GABPA antibody (ABIN969163)

Sawada, Simizu, Suzuki, Sawa, Goto, Hasegawa, Imai, Watanabe, Handa: "Synergistic transcriptional activation by hGABP and select members of the activation transcription factor/cAMP response element-binding protein family." in: The Journal of biological chemistry, Vol. 274, Issue 50, pp. 35475-82, (2000) (PubMed).

Vogel, Kristie: "The novel coactivator C1 (HCF) coordinates multiprotein enhancer formation and mediates transcription activation by GABP." in: The EMBO journal, Vol. 19, Issue 4, pp. 683-90, (2000) (PubMed).

Target Details for GABPA

Target: GABPA (GA Binding Protein Transcription Factor, alpha Subunit 60kDa (GABPA))

Alternative Name: GABPA

Background: GABPA: GA binding protein transcription factor, alpha subunit 60 kDa. It is one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, it may play a role in the Down Syndrome phenotype.

Molecular Weight: 51 kDa

Gene ID: 2551

UniProt: Q06546

Pathways: Myometrial Relaxation and Contraction