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Details for Product No. ABIN969208

Insulin-Like Growth Factor 2 MRNA Binding Protein 3 (IGF2BP3) antibody

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Antigen
Synonyms Ab2-255, RGD1306512, 2610101N11Rik, AA522010, AL022933, AU045931, IMP-3, IMP3, Koc13, Neilsen, mimp3, CT98, KOC1, VICKZ3, imp3, koc1, vera, imp-3, vg1rbp, vickz3
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 1 reference available
Catalog no. ABIN969208
Quantity 100 µL
Price
363.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 3 to 4 Business Days
Immunogen Purified recombinant fragment of human IGF2BP3 expressed in E. coli.
Clone 8F11
Isotype IgG1
Purification Ascites
Alternative Name IGF2BP3
Background Synonyms:
CT98, IMP3, KOC1, IMP-3, VICKZ3, DKFZp686F1078, IGF2BP3
The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and mηbolism. Tissue specificity: Expressed in fηl liver, fηl lung, fηl kidney, fηl thymus, fηl placenta, fηl follicles of ovary and gonocytes of testis, growing oocytes, spermatogonia and semen (at protein level). Expressed in cervix adenocarcinoma, in testicular, pancreatic and renal-cell carcinomas (at protein level). Expressed ubiquitously during fηl development at 8 and 14 weeks of gestation. Expressed in ovary, testis, brain, placenta, pancreatic cancer tissues and pancreatic cancer cell lines. IMP-3 is a marker for carcinomas and high-grade dysplastic lesions of pancreatic ductal epithelium.
Molecular Weight 69 kDa
Gene ID 10643
Application Notes Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.
Product cited in: Sitnikova, Mendese, Liu et al.: "IMP3 predicts aggressive superficial urothelial carcinoma of the bladder." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 14, Issue 6, pp. 1701-6, 2008 (PubMed).

Alternatives for antigen "Insulin-Like Growth Factor 2 MRNA Binding Protein 3 (IGF2BP3)", type "Antibodies"
Hosts (25), (6)
Reactivities (30), (17), (15), (13), (1)
Applications (19), (10), (10), (8), (7)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (4), (1), (1), (1)
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