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IGF2BP3 antibody

IGF2BP3 Reactivity: Human WB, IHC, ELISA Host: Mouse Monoclonal 8F11 unconjugated
Catalog No. ABIN969208
  • Target See all IGF2BP3 Antibodies
    IGF2BP3 (Insulin-Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3))
    Reactivity
    • 42
    • 27
    • 18
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 39
    • 3
    Mouse
    Clonality
    • 37
    • 5
    Monoclonal
    Conjugate
    • 24
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IGF2BP3 antibody is un-conjugated
    Application
    • 37
    • 13
    • 13
    • 13
    • 11
    • 7
    • 7
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human IGF2BP3 expressed in E. coli.
    Clone
    8F11
    Isotype
    IgG1
    Top Product
    Discover our top product IGF2BP3 Primary Antibody
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Sitnikova, Mendese, Liu, Woda, Lu, Dresser, Mohanty, Rock, Jiang: "IMP3 predicts aggressive superficial urothelial carcinoma of the bladder." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 14, Issue 6, pp. 1701-6, (2008) (PubMed).

  • Target
    IGF2BP3 (Insulin-Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3))
    Alternative Name
    IGF2BP3 (IGF2BP3 Products)
    Synonyms
    CT98 antibody, IMP-3 antibody, IMP3 antibody, KOC1 antibody, VICKZ3 antibody, Ab2-255 antibody, RGD1306512 antibody, imp3 antibody, koc1 antibody, vera antibody, imp-3 antibody, vg1rbp antibody, vickz3 antibody, 2610101N11Rik antibody, AA522010 antibody, AL022933 antibody, AU045931 antibody, Koc13 antibody, Neilsen antibody, mimp3 antibody, dvr1rbp antibody, wu:fb79c12 antibody, wu:fe06h09 antibody, zVg1RBP antibody, B3 antibody, IGF2 mRNA-binding protein 3-B antibody, IMP antibody, IMP-3-B antibody, Vg1 RBP-B antibody, Vg1-RBP antibody, igf2bp3 antibody, igf2bp3-a antibody, igf2bp3-b antibody, IGF2 mRNA-binding protein 3-A antibody, IMP-3-A antibody, Vg1 RBP-A antibody, vera-A antibody, insulin like growth factor 2 mRNA binding protein 3 antibody, insulin-like growth factor 2 mRNA binding protein 3 antibody, insulin like growth factor 2 mRNA binding protein 3 S homeolog antibody, insulin like growth factor 2 mRNA binding protein 3 L homeolog antibody, IGF2BP3 antibody, Igf2bp3 antibody, igf2bp3 antibody, igf2bp3.S antibody, igf2bp3.L antibody
    Background

    Description: The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism.Tissue specificity: Expressed in fetal liver, fetal lung, fetal kidney, fetal thymus, fetal placenta, fetal follicles of ovary and gonocytes of testis, growing oocytes, spermatogonia and semen (at protein level). Expressed in cervix adenocarcinoma, in testicular, pancreatic and renal-cell carcinomas (at protein level). Expressed ubiquitously during fetal development at 8 and 14 weeks of gestation. Expressed in ovary, testis, brain, placenta, pancreatic cancer tissues and pancreatic cancer cell lines .IMP-3 is a marker for carcinomas and high-grade dysplastic lesions of pancreatic ductal epithelium.

    Aliases: CT98, IMP3, KOC1, IMP-3, VICKZ3, DKFZp686F1078, IGF2BP3

    Molecular Weight
    69 kDa
    Gene ID
    10643
    HGNC
    10643
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