IGF2BP3 antibody (AA 1-100)

Catalog No. ABIN7156360

The Rabbit Polyclonal anti-IGF2BP3 antibody (ABIN7156360) specifically detects IGF2BP3 in WB, IHC, ELISA and IF. The antibody is reactive with Human samples.

Quick Overview for IGF2BP3 antibody (AA 1-100) (ABIN7156360)

Target: IGF2BP3 (Insulin-Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IGF2BP3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-IGF2BP3 Antibody

Binding Specificity: AA 1-100

Purpose: IGF2BP3 Antibody

Cross-Reactivity: Mouse

Purification: Protein G purified

Purity: >95 %

Immunogen: Recombinant Human Insulin-like growth factor 2 mRNA-binding protein 3 protein (1-100AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for IGF2BP3

Target: IGF2BP3 (Insulin-Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3))

Alternative Name: IGF2BP3

Background:

Background: RNA-binding factor that may recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript \\\'caging\\\' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation. Binds to the 3\\\'-UTR of CD44 mRNA and stabilizes it, hence promotes cell adhesion and invadopodia formation in cancer cells. Binds to beta-actin/ACTB and MYC transcripts. Binds to the 5\\\'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs.

Aliases: Cancer/testis antigen 98 antibody, CT98 antibody, DKFZp686F1078 antibody, hKOC antibody, IF2B3_HUMAN antibody, IGF II mRNA binding protein 3 antibody, IGF-II mRNA-binding protein 3 antibody, IGF2 mRNA binding protein 3 antibody, IGF2 mRNA-binding protein 3 antibody, IGF2BP3 antibody, IMP 3 antibody, IMP-3 antibody, Insulin like growth factor 2 mRNA binding protein 3 antibody, Insulin-like growth factor 2 mRNA-binding protein 3 antibody, KH domain containing protein overexpressed in cancer antibody, KH domain-containing protein overexpressed in cancer antibody, KOC 1 antibody, KOC1 antibody, VICKZ 3 antibody, VICKZ family member 3 antibody, VICKZ3 antibody

UniProt: O00425