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Details for Product No. ABIN969222

IL2-Inducible T-Cell Kinase (ITK) antibody

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Antigen
Synonyms EMT, LPFS1, LYK, PSCTK2, Emt, Tsk, Tcsk
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives ELISA, Western Blotting (WB), Immunocytochemistry (ICC), Fluorescence Microscopy (FM)
Pubmed 1 reference available
Catalog no. ABIN969222
Quantity 100 µL
Price
396.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 3 to 4 Business Days
Immunogen Purified recombinant fragment of human ITK expressed in E. coli.
Clone 5G6
Isotype IgG1
Purification Ascites
Alternative Name ITK
Background Synonyms:
EMT, LYK, PSCTK2, MGC126257, MGC126258
This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. It is thought to play a role in T-cell proliferation and differentiation.
Molecular Weight 72 kDa
Gene ID 3702
Research Area Signaling, Tyrosine Kinases
Application Notes Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000, ICC: 1/200 - 1/1000, FCM: 1/200 - 1/400
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.
Product cited in: Huck, Feyen, Niehues et al.: "Girls homozygous for an IL-2-inducible T cell kinase mutation that leads to protein deficiency develop fatal EBV-associated lymphoproliferation." in: The Journal of clinical investigation, Vol. 119, Issue 5, pp. 1350-8, 2009 (PubMed).

Alternatives for antigen "IL2-Inducible T-Cell Kinase (ITK)", type "Antibodies"
Hosts (36), (23), (14)
Reactivities (70), (21), (16), (13), (12), (12), (12)
Applications (56), (29), (10), (10), (7), (5), (4), (2), (2), (1), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (9), (5), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
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