ITK antibody (AA 2-110)

Catalog No. ABIN931475

The Mouse Monoclonal anti-ITK antibody is suitable to detect ITK in samples from Human. It has been validated for WB and ELISA.

Quick Overview for ITK antibody (AA 2-110) (ABIN931475)

Target: ITK (IL2-Inducible T-Cell Kinase (ITK))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ITK antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 5G12C4

Product Details anti-ITK Antibody

Binding Specificity: AA 2-110

Immunogen: ITK antibody was raised in Mouse using a purified recombinant fragment of ITK(aa2-110) expressed in E. coli as the immunogen.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1:10,000, WB: 1:500-1:2000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Supplied as a liquid in ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Store at -20 °C for long term storage.

Target Details for ITK

Target: ITK (IL2-Inducible T-Cell Kinase (ITK))

Alternative Name: ITK

Background: ITK is an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. It is thought to play a role in T-cell proliferation and differentiation. Synonyms: Monoclonal ITK antibody, Anti-ITK antibody, IL2 inducible T-cell kinase antibody, LYK antibody, PSCTK2 antibody, Kinase EMT, Tyrosine-protein kinase Lyk antibody, T-cell-specific kinase antibody.

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway