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Details for Product No. ABIN969338

P21-Activated Kinase 2 (PAK2) antibody

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Antigen
Synonyms PAK65, PAKgamma, gamma-PAK, 5330420P17Rik, A130002K10Rik, AI836325, D16Ertd269e, PAK-2, mKIAA4182, pak2, cb422, kinase, zgc:91798, wu:fb71h01, si:dz198m22.1, pak65, pakgamma
Reactivity
»Alternatives Human, Monkey
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
Pubmed 1 reference available
Catalog no. ABIN969338
Quantity 100 µL
Price
416.90 $   Plus shipping costs $45.00
Shipping to
Availability Will be delivered in 3 to 4 Business Days
Immunogen Purified recombinant fragment of PAK2 expressed in E. coli.
Clone 3B5
Isotype IgG1
Purification Ascites
Alternative Name PAK2
Background Synonyms:
PAK65, PAKγ
PAK2, also known as P21 (CDKN1A) -activated kinase 2. The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. PAK2 is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. PAK2 has been shown to interact with SH3KBP1, CDC42 and Abl gene.
Molecular Weight 61 kDa
Gene ID 5062
Research Area Cancer, Apoptosis/Necrosis, Tyrosine Kinases, Kinases/Phosphatases
Application Notes Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, ICC: 1/200 - 1/1000
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.
Product cited in: Chu, Wu, Liao et al.: "A novel role for p21-activated protein kinase 2 in T cell activation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 172, Issue 12, pp. 7324-34, 2004 (PubMed).

Alternatives for antigen "P21-Activated Kinase 2 (PAK2)", type "Antibodies"
Hosts (150), (11)
Reactivities (156), (113), (112), (37), (36), (12), (4), (1), (1)
Applications (125), (82), (45), (32), (30), (8), (6), (5), (2), (2), (2), (1)
Conjugates (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3)
Epitopes (23), (19), (17), (17), (10), (5), (4), (2), (2), (2), (1), (1), (1), (1), (1), (1)
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