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P21-Activated Kinase 2 (PAK2) antibody

Antigen

P21-Activated Kinase 2 (PAK2)
Synonyms PAK65, PAKgamma, gamma-PAK, PAK-2, AI836325, KIAA4182, mKIAA4182, D16Ertd269e, A130002K10Rik, pak2, cb422, kinase, zgc:91798, wu:fb71h01, si:dz198m22.1, PAK2
Clonality Monoclonal (3B5)
Host
Alternatives

Mouse
Reactivity
Alternatives

Human, Monkey
Conjugate
Alternatives Un-conjugated
Application
Alternatives ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
1 reference available
Catalog no. ABIN969338
Quantity 0.1ml  (Variants)
Price 416.90 $   Plus shipping costs $45.00
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Additional Information
Application Details Publications Alternatives Variants back to top

Alternative name PAK2
Gene ID 5062
Immunogen Purified recombinant fragment of PAK2 expressed in E. Coli.
Format Liquid
Isotype IgG1
Clone 3B5
Description PAK2, also known as P21 (CDKN1A)-activated kinase 2. The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. PAK2 is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. PAK2 has been shown to interact with SH3KBP1, CDC42 and Abl gene.
Synonyms: PAK65, PAKgamma
Molecular Weight 61kDa

Application Details
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Application Notes Western Blotting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
Immunofluorescence: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Purification Ascites
Buffer Ascitic fluid containing 0.03% sodium azide.
Preservative 0.03% sodium azide
Storage Store at 4℃, for long term storage, store at -20℃.
Research Area Cancer, Apoptosis/Necrosis, Tyrosine Kinases, Kinases/Phosphatases
Restrictions For Research Use only

Publications
Application Details Alternatives Variants back to top

Product Chu, Wu, Liao et al.: "A novel role for p21-activated protein kinase 2 in T cell activation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 172, Issue 12, pp. 7324-34, 2004 (PubMed).

Alternatives
Application Details Publications Variants back to top

Alternatives for antigen "P21-Activated Kinase 2 (PAK2)", type "Antibodies"
Hosts Rabbit (92), Mouse (4)
Reactivities Human (91), Rat (Rattus) (63), Mouse (Murine) (62), Cat (Feline) (1), Chicken (1), Cow (Bovine) (1), Dog (Canine) (1), Monkey (1), Primate (1), Rabbit (1)
Applications Western Blotting (WB) (69), ELISA (41), Immunofluorescence (IF) (30), Immunohistochemistry (IHC) (19), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (17), Immunoprecipitation (IP) (5), Immunocytochemistry (ICC) (4), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Flow Cytometry (FACS) (1), Immunoelectron Microscopy (IEM) (1)
Conjugates Alexa Fluor 350 (3), Alexa Fluor 488 (3), Alexa Fluor 555 (3), Alexa Fluor 647 (3), PE,Cy5.5 (3), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy7 (1)
Epitopes N-Term (17), C-Term (8), pSer20 (7), pSer141 (5), Internal Region (4), pSer192,Internal Region (3), AA 125-175 (1), AA 25-75 (1), pSer144 (1), pSer197 (1), pThr402,pThr423 (1)