P21-Activated Kinase 2 (PAK2) antibody

Details for Product No. ABIN969338
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Synonyms pak2, cb422, kinase, zgc:91798, wu:fb71h01, si:dz198m22.1, pak65, pakgamma, PAK65, PAKgamma, 5330420P17Rik, A130002K10Rik, AI836325, D16Ertd269e, PAK-2, mKIAA4182, gamma-PAK, PAKI, Pak3
Human, Monkey
(203), (104), (104), (5), (1), (1), (1)
(190), (14)
Clonality (Clone)
Monoclonal ()
(6), (6), (6), (4), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2)
ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
(173), (106), (73), (26), (20), (14), (10), (6), (3), (3), (3), (2), (1), (1)
Pubmed 1 reference available
Quantity 100 μL
Shipping to United States (Change)
Availability Will be delivered in 3 to 4 Business Days
Request Want additional data for this product?

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Catalog No. ABIN969338
453.20 $
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Immunogen Purified recombinant fragment of PAK2 expressed in E. coli.
Clone 3B5
Isotype IgG1
Purification Ascites
Alternative Name PAK2
Background Synonyms:
PAK2, also known as P21 (CDKN1A) -activated kinase 2. The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. PAK2 is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. PAK2 has been shown to interact with SH3KBP1, CDC42 and Abl gene.
Molecular Weight 61 kDa
Gene ID 5062
Research Area Cancer, Apoptosis/Necrosis, Tyrosine Kinases, Kinases/Phosphatases
Application Notes Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, ICC: 1/200 - 1/1000
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.
Supplier Images
anti-P21-Activated Kinase 2 (PAK2) antibody Figure 3: Confocal immunofluorescence analysis of Hela cells using PAK2 mouse mAb (green) . Blue: DRAQ5 fluorescent DNA dye.
anti-P21-Activated Kinase 2 (PAK2) antibody (2) Figure 2: Immunohistochemical analysis of paraffin-embedded human lung cancer (left) and gastric cancer (right) using PAK2 mouse mAb with DAB staining.
anti-P21-Activated Kinase 2 (PAK2) antibody (3) Figure 1: Western blot analysis using PAK2 mouse mAb against Hela (1), Jurkat (2), A549 (3), HEK293 (4) and K562 (5) cell lysate.
Product cited in: Chu, Wu, Liao et al.: "A novel role for p21-activated protein kinase 2 in T cell activation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 172, Issue 12, pp. 7324-34, 2004 (PubMed).

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