Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) antibody

Details for Product No. ABIN969539, Supplier: Log in to see
Antigen
  • SLN-1
  • SLN1
  • STR-1
  • Stmy1
  • Str1
  • CHDS6
  • MMP-3
  • SL-1
  • STMY
  • STMY1
  • STR1
  • MMP10
  • MMP3
  • matrix metallopeptidase 3
  • matrix metallopeptidase 3 (stromelysin 1, progelatinase)
  • matrix metallopeptidase 10 (stromelysin 2)
  • Mmp3
  • MMP3
  • MMP10
Reactivity
Human
372
77
76
15
11
7
6
5
4
1
1
1
1
1
1
Host
Mouse
209
174
22
5
2
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
22
21
19
9
6
6
6
6
5
5
4
3
3
3
3
3
3
3
3
3
2
2
2
1
1
1
1
1
1
Application
Flow Cytometry (FACS), ELISA, Western Blotting (WB)
309
181
142
106
57
44
34
28
26
13
10
10
2
1
1
1
Options
Supplier
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Immunogen Purified recombinant fragment of human MMP3 expressed in E. Coli.
Clone 4F10
Isotype IgG1
Purification Purified
Alternative Name MMP3 (MMP3 Antibody Abstract)
Background Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
Molecular Weight 54 kDa
Gene ID 4314
HGNC 4314
Research Area Cardiovascular, Atherosclerosis, Proteolysis / Ubiquitin, Metalloprotease, Angiogenesis, Extracellular Matrix, Matrix Metalloproteinases
Application Notes ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400
Restrictions For Research Use only
Format Liquid
Buffer PBS with 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 4°C, -20°C for long term storage
Supplier Images
ELISA image for anti-Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) antibody (ABIN969539) Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 n...
Flow Cytometry (FACS) image for anti-Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) antibody (ABIN969539) Figure 2: Flow cytometric analysis of NIH/3T3 cells using MMP3 mouse mAb (green) and ...
Western Blotting (WB) image for anti-Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) antibody (ABIN969539) Figure 3: Western blot analysis using MMP3 mAb against human MMP3 (AA: 189-441) recom...
Product cited in: Jin, Miao, Hu, Xu, Huang, Chen, Tian, Wei, Boffetta, Shen: "Putative functional polymorphisms of MMP9 predict survival of NSCLC in a Chinese population." in: International journal of cancer. Journal international du cancer, Vol. 124, Issue 9, pp. 2172-8, 2009 (PubMed).

Nan, Niu, Hunter, Han: "Missense polymorphisms in matrix metalloproteinase genes and skin cancer risk." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 17, Issue 12, pp. 3551-7, 2008 (PubMed).