COPS5 antibody (N-Term)
Quick Overview for COPS5 antibody (N-Term) (ABIN182685)
Target
See all COPS5 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- N-Term
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Sequence
- NMQEAQSIDE IYKYDKKQQQ EILAAKPWTK DHHYFKYCKI SALALLKMVM
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Characteristics
- This is a rabbit polyclonal antibody against COPS5. It was validated on Western Blot and immunohistochemistry.
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Purification
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human COPS5
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anti-COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5) antibody
COPS5 Reactivity: Human WB, IHC, IF, ChIP Host: Rabbit Monoclonal unconjugated
anti-COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5) (AA 1-334) antibodyCOPS5 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5) (AA 1-334) antibodyCOPS5 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5) antibodyCOPS5 Reactivity: Human, Mouse, Rat IF Host: Rabbit Polyclonal unconjugated
anti-COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5) (Internal Region) antibodyCOPS5 Reactivity: Human, Mouse, Rat WB, IHC, IF, ELISA, ICC Host: Rabbit Polyclonal unconjugated
anti-COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5) antibodyCOPS5 Reactivity: Human, Mouse WB, IHC, IP, IHC (p) Host: Mouse Monoclonal 8H8-5 unconjugated
anti-COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5) (AA 8-334) antibodyCOPS5 Reactivity: Human, Mouse, Rat WB, IHC, IF, IP, ICC, IHC (fro), FACS Host: Rabbit Polyclonal unconjugated
anti-COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5) (N-Term) antibodyCOPS5 Reactivity: Human, Mouse, Rat, Pig, Horse, Guinea Pig, Rabbit WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5) (Internal Region) antibodyCOPS5 Reactivity: Human WB, IHC, IP, IHC (p) Host: Mouse Monoclonal unconjugated
anti-COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5) antibodyCOPS5 Reactivity: Human, Mouse WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 334 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- COPS5 (COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5))
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Alternative Name
- COPS5
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Background
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The protein encoded by COPS5 is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors.
Alias Symbols: CSN5, JAB1, SGN5, MOV-34
Protein Interaction Partner: COPS6, UBC, CUL1, NEDD8, PTGS2, GPS1, LRP1, RANBP9, APP, SIAH1, BACE1, CTNNB1, COPS5, STAT3, CREB3, COPS4, SART3, COPS3, EPB41L1, CAST, KIF5B, PDLIM7, SMAD4, FBXO6, COPS2, TYK2, CDK2, CENPW, CENPT, FBXW4, MYEOV2, COPS8, CHUK, IKBKB, DTL, CD93, DDO, SMAD2,
Protein Size: 334 -
Molecular Weight
- 38 kDa
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Gene ID
- 10987
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NCBI Accession
- NM_006837, NP_006828
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UniProt
- Q92905
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Pathways
- Cell Division Cycle
Target
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