NFKBIA antibody
Quick Overview for NFKBIA antibody (ABIN155061)
Target
See all NFKBIA AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
-
-
Specificity
- The antibody detects both phosphorylated and non-phosphorylated forms of IκB-alpha.
-
Characteristics
- Synonyms: I-kappa-B-alpha, MAD3, NFKBI, I kappa B-alpha, IkappaBalpha, IkB-alpha, NF-kappa-Binhibitor alpha, Major histocompatibility complex enhancer-binding protein MAD3
-
Purification
- Immunoaffinity Chromatography.
-
Immunogen
- Recombinant Human IkBa
-
Isotype
- IgG1
-
-
anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA) (N-Term) antibody
NFKBIA Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA) (AA 74-247) antibodyNFKBIA Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA) (pSer32), (pSer36) antibodyNFKBIA Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA) (AA 1-317) antibodyNFKBIA Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA) (AA 150-291) antibodyNFKBIA Reactivity: Human IHC, ELISA, FACS, ICC Host: Mouse Monoclonal 4D4C4 unconjugated
anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA) (AA 3-112) antibodyNFKBIA Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA) (AA 1-317) antibodyNFKBIA Reactivity: Human WB, ELISA, IF Host: Mouse Monoclonal 3H4 unconjugated
anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA) (AA 1-120) antibodyNFKBIA Reactivity: Human, Mouse, Rat, Cow, Chicken WB, ELISA, IF (p), IF (cc), FACS, IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA) antibodyKD Validated NFKBIA Reactivity: Human WB, IF (p), FACS Host: Rabbit Monoclonal 25GB4040 unconjugated Recombinant Antibody
anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA) (Center) antibodyNFKBIA Reactivity: Human, Mouse WB, IF, IHC (p), ICC Host: Rabbit Polyclonal unconjugated
-
-
Application Notes
-
Western Blot: 0.5-4 μg/mL. Immunoprecipitation: 1-4 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
-
-
-
Concentration
- 0.25 mg/mL
-
Buffer
- PBS, pH 7.2, containing 50 % Glycerol, 1 % BSA and 0.02 % Thimerosal.
-
Preservative
- Thimerosal (Merthiolate)
-
Precaution of Use
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Storage
- -20 °C/-80 °C
-
Storage Comment
-
Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -20 °C to-70 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
Expiry Date
- 12 months
-
-
- NFKBIA (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA))
-
Alternative Name
- NFKBIA / IKBA
-
Background
- NF-κB is silenced in the cytoplasm by an inhibitory protein, IκB. IκB proteins are phosphorylated by IκB kinase complex consisting of at least three proteins, IKK1/α, IKK2/β, and IKK3/γ. External stimuli such TNF-α or other cytokines results in phosphorylation and degradation of IκB releasing NF-κB dimers. NF-κB dimer subsequently translocates to the nucleus and activates target genes. Six members of IκB family members have been identified. One of the first gene induced following NF-κB activation is IκBα.Synonyms: I kappa B-alpha, I-kappa-B-alpha, IkB-alpha, IkappaBalpha, MAD3, Major histocompatibility complex enhancer-binding protein MAD3, NF-kappa-B inhibitor alpha, NFKBI
-
Gene ID
- 4792
-
UniProt
- P25963
-
Pathways
- NF-kappaB Signaling, TCR Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Maintenance of Protein Location, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, BCR Signaling
Target
-
