NFKBIA antibody
Quick Overview for NFKBIA antibody (ABIN127058)
Target
See all NFKBIA AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Specificity
- This antibody detects IκB-alpha.
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Purification
- Affinity purified
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anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA) (N-Term) antibody
NFKBIA Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA) (AA 74-247) antibodyNFKBIA Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA) (pSer32), (pSer36) antibodyNFKBIA Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA) (AA 1-317) antibodyNFKBIA Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA) (AA 150-291) antibodyNFKBIA Reactivity: Human IHC, ELISA, FACS, ICC Host: Mouse Monoclonal 4D4C4 unconjugated
anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA) (AA 3-112) antibodyNFKBIA Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA) (AA 1-317) antibodyNFKBIA Reactivity: Human WB, ELISA, IF Host: Mouse Monoclonal 3H4 unconjugated
anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA) (AA 1-120) antibodyNFKBIA Reactivity: Human, Mouse, Rat, Cow, Chicken WB, ELISA, IF (p), IF (cc), FACS, IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA) antibodyKD Validated NFKBIA Reactivity: Human WB, IF (p), FACS Host: Rabbit Monoclonal 25GB4040 unconjugated Recombinant Antibody
anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA) (Center) antibodyNFKBIA Reactivity: Human, Mouse WB, IF, IHC (p), ICC Host: Rabbit Polyclonal unconjugated
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Application Notes
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Western Blot: 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 0.2 mg/mL
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Buffer
- PBS, pH 7.2, containing 50 % glycerol, 1 % BSA, 0.02 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- -20 °C/-80 °C
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Storage Comment
- Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
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- NFKBIA (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA))
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Alternative Name
- NFKBIA / IKBA
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Background
- IκB-alpha protein is a NF-κB inhibitory protein. It binds NF-κB and retains the complex in the cytoplasm, thereby preventing it from entering into nucleus and functioning as a transcription factor. Upon receiving a variety of signals, IκB-alpha undergoes phosphorylation at serine residues by an ubiquitin-dependent protein kinases and finally degraded by the proteasome. Free NF-κB then binds DNA and affects gene expression.Synonyms: I kappa B-alpha, I-kappa-B-alpha, IkB-alpha, IkappaBalpha, MAD3, Major histocompatibility complex enhancer-binding protein MAD3, NF-kappa-B inhibitor alpha, NFKBI
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Gene ID
- 18035
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NCBI Accession
- NP_035037
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UniProt
- Q9Z1E3
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Pathways
- NF-kappaB Signaling, TCR Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Maintenance of Protein Location, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, BCR Signaling
Target
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