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Caspase 12 (Gene/pseudogene) ELISA Kits (CASP12)
On are 6 Caspase 12 (Gene/pseudogene) (CASP12) ELISA Kits from 3 different suppliers available. Additionally we are shipping Caspase 12 Antibodies (24) and and many more products for this protein. A total of 32 Caspase 12 products are currently listed.
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CASP12 120329

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Top referenced Caspase 12 ELISA Kits

  1. Rat (Rattus) Caspase 12 ELISA Kit for Sandwich ELISA - ABIN811977 : Saeed, El-Naga, El-Bakly, Abdel-Rahman, Salah ElDin, El-Demerdash: Epigallocatechin-3-gallate pretreatment attenuates doxorubicin-induced cardiotoxicity in rats: A mechanistic study. in Biochemical pharmacology 2015 (PubMed)

More ELISA Kits for Caspase 12 Interaction Partners

Human Caspase 12 (Gene/pseudogene) (CASP12) interaction partners

  1. Endoplasmic reticulum stress related factor ATF6 (show ATF6 ELISA Kits) and caspase-12 trigger apoptosis in neonatal hypoxic-ischemic encephalopathy.

  2. Expression of caspase-12 was linked to decreased systemic and adipose tissue inflammation in a cohort of African American obese children.

  3. We found that RNA interference-induced Caspase-12 silencing increased NOD1 (show NOD1 ELISA Kits), hBD1 (show DEFB1 ELISA Kits) and hBD2 (show DEFB4 ELISA Kits) expression

  4. EtOH-induced activation of caspase-12 could be one of the underlying mechanisms of hepatocyte apoptosis.

  5. Distribution of CASP12 alleles (#rs497116) in African-Americans (AA) with rheumatoid arthritis (RA). There was no difference in the overall distribution of genotypes within AA with RA, but homozygous patients had lower baseline joint-narrowing scores.

  6. CASPASE-12 does not influence the susceptibility to Candida sepsis, nor has any effect on the serum cytokine concentrations in Candida sepsis patients during the course of infection.

  7. examines the role that CASP12 plays in down-regulating inflammation, we hypothesize that pathogens which exploit the inflammatory response are restrained by an active CASP12 gene product

  8. caspase 12 has acquired deleterious mutations

  9. Pathways involving this enzyme are involved in a neurodegenerative disease in vivo, and thus offer novel potential targets for the treatment of prion (show PRNP ELISA Kits) disorders.

  10. Na/Ca exchanger (show SLC8A1 ELISA Kits) overexpression activates caspase-12

Caspase 12 (CASP12) Antigen Profile

Antigen Summary

Caspases are cysteine proteases that cleave C-terminal aspartic acid residues on their substrate molecules. This gene is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. In rodents, the homolog of this gene mediates apoptosis in response to endoplasmic reticulum stress. However, in humans this gene contains a polymorphism for the presence or absence of a premature stop codon. The majority of human individuals have the premature stop codon and produce a truncated non-functional protein. The read-through codon occurs primarily in individuals of African descent and carriers have endotoxin hypo-responsiveness and an increased susceptibility to severe sepsis. Several alternatively spliced transcript variants have been noted for this gene.

Alternative names and synonyms associated with Caspase 12 (CASP12)

  • caspase 12 (gene/pseudogene) (CASP12) Elisa Kit
  • CASP-12 Elisa Kit
  • CASP12P1 Elisa Kit

Protein level used designations for CASP12

caspase 12 pseudogene 1 , inactive caspase-12

120329 Homo sapiens
100506742 Homo sapiens
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