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Caspase 2 Proteins

(Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2))
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011].

12 results

CASP2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Catalog No. ABIN1348098
 
CASP2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Catalog No. ABIN1348097
 
CASP2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 80 % by SDS - PAGE SDS
Catalog No. ABIN5853713
 
CASP2 Origin: Human Host: Escherichia coli (E. coli) Recombinant SDS, WB, ELISA
Catalog No. ABIN7575318
 
CASP2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, Imm, PC
Catalog No. ABIN7419970
 
CASP2 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, Imm, PC
Catalog No. ABIN7405921
 
CASP2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 80 % pure SDS
Catalog No. ABIN2128316
 
CASP2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, Imm, PC
Catalog No. ABIN7389635
 
CASP2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Catalog No. ABIN5709201
 
CASP2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Active
Catalog No. ABIN925026
 
CASP2 Origin: Rat Host: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN7583748
 
CASP2 Origin: Chicken Host: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN1645134
 
  • Type Protein
    • Protein
  • Application
    • SDS-PAGE (SDS)
    • Western Blotting (WB)
    • ELISA
    • Immunogen (Imm)
    • Positive Control (PC)
    • Affinity Purification (AP)
    • Antibody Array (AA)
  • Reactivity
    • Human
    • Chicken
    • Mouse
    • Rat
  • Images available
  • Carrier free only
  • Host
    • Escherichia coli (E. coli)
    • Wheat germ
    • Yeast
  • Binding Specificity
    • AA 170-325
    • AA 1-452
    • AA 121-220
    • AA 141-308
    • AA 170-333
    • AA 2-452
    • AA 334-452
    • AA 348-452
  • Conjugate
    • His tag
    • GST tag
    • Un-conjugated
    • His tag,GST tag
    • His-SUMO Tag
  • Protein Type
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • Biological Activity
    • Biologically Active
  • Supplier
    • antibodies-online
    • CUSABIO
    • Kamiya Biomedicals
    • Signalway

Latest Publications for our Caspase 2 Proteins

Murakami, Tolstykh, Bao, Niu, Steuer, Bao, Chang, Espiritu, Bansal, Lam, Otto, Sofia, Furman: "Mechanism of activation of PSI-7851 and its diastereoisomer PSI-7977." in: The Journal of biological chemistry, Vol. 285, Issue 45, pp. 34337-47, (2010) (PubMed).

Chen, Xia, Fang, Hawke, Lu: "Caspase-10-mediated heat shock protein 90 beta cleavage promotes UVB irradiation-induced cell apoptosis." in: Molecular and cellular biology, Vol. 29, Issue 13, pp. 3657-64, (2009) (PubMed).

Hasegawa, Yamada, Komiyama, Hayashi, Ishibashi, Sunazuka, Izuhara, Sugahara, Tsuruda, Masuda, Takasu, Tsukasaki, Tomonaga, Kamihira et al.: "A novel natural compound, a cycloanthranilylproline derivative (Fuligocandin B), sensitizes leukemia cells to apoptosis induced by tumor necrosis factor related apoptosis-inducing ligand (TRAIL) ..." in: Blood, Vol. 110, Issue 5, pp. 1664-74, (2007) (PubMed).

Basu, Lu, Sun, Moor, Akkaraju, Huang: "Proteolytic activation of protein kinase C-epsilon by caspase-mediated processing and transduction of antiapoptotic signals." in: The Journal of biological chemistry, Vol. 277, Issue 44, pp. 41850-6, (2002) (PubMed).

Aliases for Caspase 2 Proteins

caspase 2 (CASP2) Proteins
caspase 2 L homeolog (casp2.L) Proteins
caspase-2 (CpipJ_CPIJ008254) Proteins
caspase 2 (Casp2) Proteins
CASP-2 Proteins
Caspase-2 Proteins
ICH-1 Proteins
ICH-1L/1S Proteins
ICH1 Proteins
ICH1L1S Proteins
NEDD-2 Proteins
Nedd2 Proteins
NEDD2 Proteins
PPP1R57 Proteins
xCaspase-2 Proteins
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