|Antigen||Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25) Antibodies|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This TNFRSF25 antibody is un-conjugated Alternatives|
Enzyme Immunoassay (EIA), Western Blotting (WB)
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Product Details anti-TNFRSF25 AntibodyTarget Details TNFRSF25 Application Details Handling Images
|Specificity||DR3 antibody was raised against a peptide corresponding to amino acids 398 to 417 of human DR3.|
|Immunogen||Human DR3 (C-Terminus) Peptide|
Target Details TNFRSF25Product Details anti-TNFRSF25 Antibody Application Details Handling Images back to top
|Alternative Name||TNFRSF25 / DR3 / TRAMP (TNFRSF25 Antibody Abstract)|
|Background||Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNFR1 and Fas. A novel cell death receptor was recently identified by several groups independently and designated DR3, Wsl-1, Apo-3, TRAMP and LARD1-5. The ligand for this novel cell death receptor has not yet been defined. DR3 is highly expressed in the tissues enriched in lymphocytes including PBL, thymus and spleen. Like TNFR1, DR3 induces apoptosis and NF-kappaB activation.Synonyms: AIR, APO3, Apo-3, Apoptosis-inducing receptor AIR, Apoptosis-mediating receptor DR3, Apoptosis-mediating receptor TRAMP, DDR3, Death receptor 3, LARD, Lymphocyte-associated receptor of death, Protein WSL, Protein WSL-1, TNFRSF12, Tumor necrosis factor receptor superfamily member 25, WSL, WSL1|
Application DetailsProduct Details anti-TNFRSF25 Antibody Target Details TNFRSF25 Handling Images back to top
ELISA. Western Blot: 1/500 to 1/1000. A 59 kDa band should be detected and has no crossreaction to other death receptors.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-TNFRSF25 Antibody Target Details TNFRSF25 Application Details Images back to top
|Buffer||PBS containing 0.02 % sodium azide.|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Storage Comment||Store the antibody undiluted at 2-8 °C.|