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TRAIL Proteins

(Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10))
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. This protein binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly also to TNFRSF11B/OPG. The activity of this protein may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and TNFRSF11B/OPG that cannot induce apoptosis. The binding of this protein to its receptors has been shown to trigger the activation of MAPK8/JNK, caspase 8, and caspase 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010].

Active filters:

  • Target: TRAIL (TNFSF10)
  • Protein
Catalog no. Product Reactivity Host / Clonality Application Price & lead time
ABIN7275775
TRAIL Protein (AA 118-281, Trimer) (His-DYKDDDDK Tag) TNFSF10 · Protein Human HEK-293 Cells
  • SDS (SDS-PAGE: Validation image available)
  • ELISA (ELISA: Validation image available)
  • SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: Validation image available)
$234.17 View price
  • 100 μg
  • 500 μg
Delivery in 11 to 14 Business Days Shipping to: United States
ABIN1323209
TRAIL Protein (AA 1-281) (GST tag) TNFSF10 · Protein Human Wheat germ
  • AP (Affinity Purification: Listed application)
  • AA (Antibody Array: Listed application)
  • ELISA (ELISA: Listed application)
  • WB (Western Blotting: Listed application)
$475.39 View price
  • 10 μg
  • 25 μg
Delivery in 11 to 14 Business Days Shipping to: United States
ABIN4369885
TRAIL Protein (AA 114-281) (His-DYKDDDDK-Strep II Tag) TNFSF10 · Protein Human HEK-293T Cells
  • SDS (SDS-PAGE: Validation image available)
  • WB (Western Blotting: Validation image available)
  • ELISA (ELISA: Listed application)
  • PI (Protein Interaction: Listed application)
$671.24 View price
  • 2 μg
  • 25 μg
Delivery in 11 to 14 Business Days Shipping to: United States
ABIN7275783
TRAIL Protein (AA 118-291) (His tag) TNFSF10 · Protein Mouse Escherichia coli (E. coli)
  • SDS (SDS-PAGE: Validation image available)
$296.00 View price
  • 100 μg
  • 500 μg
Delivery in 11 to 14 Business Days Shipping to: United States
ABIN7125525
TRAIL Protein (AA 95-281) (His-IF2DI Tag) TNFSF10 · Protein Human Escherichia coli (E. coli)
  • WB (Western Blotting: Validation image available)
  • ELISA (ELISA: Listed application)
$510.30 View price
  • 50 μg
  • 1 mg
  • 200 μg
Delivery in 13 to 17 Business Days Shipping to: United States
ABIN666704
TRAIL Protein (AA 114-281) TNFSF10 · Protein Human Escherichia coli (E. coli)
  • SDS (SDS-PAGE: Validation image available)
$503.85 View price
  • 100 μg
  • 20 μg
  • 500 μg
Delivery in 15 to 21 Business Days Shipping to: United States
ABIN8117973
TRAIL Protein (AA 114-281) (mFc Tag) TNFSF10 · Protein Human Mammalian Cells
  • SDS (SDS-PAGE: Validation image available)
$404.89 View price
  • 100 μg
  • 1 mg
  • 20 μg
Delivery in 23 to 40 Business Days Shipping to: United States
ABIN1097691
TRAIL Protein (AA 115-281) TNFSF10 · Protein Human Escherichia coli (E. coli)
  • Func (Functional Studies: Listed application)
$263.28 View price
  • 50 μg
  • 1 mg
  • 10 μg
  • 500 μg
Delivery in 4 to 5 Business Days Shipping to: United States
ABIN3098448
TRAIL Protein (AA 1-281) (Strep Tag) TNFSF10 · Protein Human Cell-free protein synthesis (CFPS)
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
  • ELISA (ELISA: Listed application)
starts at $19,692.86 View price
  • 250 μg
  • 500 μg
Delivery in 55 to 67 Business Days Shipping to: United States
ABIN3134332
TRAIL Protein (AA 1-291) (Strep Tag) TNFSF10 · Protein Mouse Cell-free protein synthesis (CFPS)
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
  • ELISA (ELISA: Listed application)
starts at $19,692.86 View price
  • 250 μg
  • 500 μg
Delivery in 55 to 67 Business Days Shipping to: United States
ABIN1344414
TRAIL Protein (AA 95-281, Extracellular Domain, N-Term, Soluble) (DYKDDDDK Tag) TNFSF10 · Protein Human, Mouse Escherichia coli (E. coli)
  • SDS (SDS-PAGE: Listed application)
$172.50 View price
  • 10 μg
Delivery in 5 to 10 Business Days Shipping to: United States
ABIN2018415
TRAIL Protein (AA 114-281) TNFSF10 · Protein Human Escherichia coli (E. coli)
$161.87 View price
  • 50 μg
  • 1 mg
  • 10 μg
Delivery in 2 to 4 Business Days Shipping to: United States
ABIN7866079
TRAIL Protein (AA 1-281) TNFSF10 · Protein Human Escherichia coli (E. coli)
$128.19 View price
  • 10 μg
Delivery in 9 to 12 Business Days Shipping to: United States
ABIN7866080
TRAIL Protein (AA 1-291) TNFSF10 · Protein Mouse Escherichia coli (E. coli)
$128.19 View price
  • 10 μg
Delivery in 9 to 12 Business Days Shipping to: United States
ABIN7884590
TRAIL Protein (His tag) TNFSF10 · Protein Mouse Escherichia coli (E. coli)
  • WB (Western Blotting: Listed application)
$297.95 View price
  • 5 μg
Delivery in 10 to 15 Business Days Shipping to: United States
ABIN7884589
TRAIL Protein (His tag) TNFSF10 · Protein Human Escherichia coli (E. coli)
  • WB (Western Blotting: Listed application)
$297.95 View price
  • 5 μg
Delivery in 10 to 15 Business Days Shipping to: United States
ABIN7669868
TRAIL Protein (AA 118-291) (TRX tag) TNFSF10 · Protein Mouse Escherichia coli (E. coli)
  • Imm (Immunogen: Listed application)
$1,902.46 View price
  • 500 μg
Delivery in 11 to 15 Business Days Shipping to: United States
ABIN7669867
TRAIL Protein (AA 118-291) (GST tag) TNFSF10 · Protein Mouse Escherichia coli (E. coli)
  • Imm (Immunogen: Listed application)
$1,902.46 View price
  • 500 μg
Delivery in 11 to 15 Business Days Shipping to: United States
ABIN1330586
TRAIL Protein TNFSF10 · Protein Human Wheat germ
  • AP (Affinity Purification: Listed application)
  • Func (Functional Studies: Listed application)
  • ScA (Screening Assay: Listed application)
$799.44 View price
  • 10 μg
Delivery in 11 to 14 Business Days Shipping to: United States
ABIN7669866
TRAIL Protein (His tag) TNFSF10 · Protein Mouse Escherichia coli (E. coli)
  • CC (Cell Culture: Listed application)
$307.73 View price
  • 20 μg
Delivery in 11 to 15 Business Days Shipping to: United States
Protein
  • SDS (SDS-PAGE: Validation image available)
  • ELISA (ELISA: Validation image available)
  • SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: Validation image available)
Origin
Human
Host
HEK-293 Cells
Protein Type
Recombinant
Purity
> 95 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC
Catalog No. ABIN7275775
$234.17
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 11 to 14 Business Days
Protein
  • AP (Affinity Purification: Listed application)
  • AA (Antibody Array: Listed application)
  • ELISA (ELISA: Listed application)
  • WB (Western Blotting: Listed application)
Origin
Human
Host
Wheat germ
Protein Type
Recombinant
Catalog No. ABIN1323209
$475.39
Plus shipping costs $50.00, if applicable $20.00 dry ice
10 μg (More quantities available)
Shipping to: United States
Delivery in 11 to 14 Business Days
Protein
  • SDS (SDS-PAGE: Validation image available)
  • WB (Western Blotting: Validation image available)
  • ELISA (ELISA: Listed application)
  • PI (Protein Interaction: Listed application)
Origin
Human
Host
HEK-293T Cells
Protein Type
Recombinant
Catalog No. ABIN4369885
$671.24
Plus shipping costs $50.00, if applicable $20.00 dry ice
2 μg
Shipping to: United States
Delivery in 11 to 14 Business Days
Protein
  • SDS (SDS-PAGE: Validation image available)
Origin
Mouse
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Purity
> 95 % as determined by Tris-Bis PAGE
Catalog No. ABIN7275783
$296.00
Plus shipping costs $50.00, if applicable $20.00 dry ice
100 μg (More quantities available)
Shipping to: United States
Delivery in 11 to 14 Business Days
Protein
  • WB (Western Blotting: Validation image available)
  • ELISA (ELISA: Listed application)
Origin
Human
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Purity
Greater than 90 % as determined by SDS-PAGE.
Catalog No. ABIN7125525
$510.30
Plus shipping costs $50.00
50 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 17 Business Days
Protein
  • SDS (SDS-PAGE: Validation image available)
Origin
Human
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Purity
> 95 %
Catalog No. ABIN666704
$503.85
Plus shipping costs $50.00, if applicable $20.00 dry ice
100 μg (More quantities available)
Shipping to: United States
Delivery in 15 to 21 Business Days
Protein
  • SDS (SDS-PAGE: Validation image available)
Origin
Human
Host
Mammalian Cells
Protein Type
Recombinant
Purity
Greater than 95 % as determined by SDS-PAGE.
Catalog No. ABIN8117973
$404.89
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 23 to 40 Business Days
Protein
  • Func (Functional Studies: Listed application)
Origin
Human
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Purity
> 95 % as determined by reducing SDS-PAGE.
Biological Activity
Active
Catalog No. ABIN1097691
$263.28
Plus shipping costs $50.00
50 μg (More quantities available)
Shipping to: United States
Delivery in 4 to 5 Business Days
Protein
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
  • ELISA (ELISA: Listed application)
Grade
custom-made
Origin
Human
Host
Cell-free protein synthesis (CFPS)
Protein Type
Recombinant
Purity
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Catalog No. ABIN3098448
starts at
$19,692.86
Plus shipping costs $50.00, if applicable $20.00 dry ice
250 μg
Shipping to: United States
Delivery in 55 to 67 Business Days
Protein
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
  • ELISA (ELISA: Listed application)
Grade
custom-made
Origin
Mouse
Host
Cell-free protein synthesis (CFPS)
Protein Type
Recombinant
Purity
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Catalog No. ABIN3134332
starts at
$19,692.86
Plus shipping costs $50.00, if applicable $20.00 dry ice
250 μg
Shipping to: United States
Delivery in 55 to 67 Business Days
Protein
  • SDS (SDS-PAGE: Listed application)
Origin
Human, Mouse
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Purity
>95 % (SDS-PAGE)
Biological Activity
Active
Catalog No. ABIN1344414
$172.50
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 5 to 10 Business Days
Protein
Origin
Human
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Purity
> 95 % as analyzed by SDS-PAGE and HPLC.
Biological Activity
Active
Catalog No. ABIN2018415
$161.87
Plus shipping costs $50.00
50 μg (More quantities available)
Shipping to: United States
Delivery in 2 to 4 Business Days
Protein
Origin
Human
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Purity
>95 % , as determined by SDS-PAGE and HPLC
Biological Activity
Active
Catalog No. ABIN7866079
$128.19
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 9 to 12 Business Days
Protein
Origin
Mouse
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Purity
>95 % , as determined by SDS-PAGE and HPLC
Biological Activity
Active
Catalog No. ABIN7866080
$128.19
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 9 to 12 Business Days
Protein
  • WB (Western Blotting: Listed application)
Origin
Mouse
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Purity
>98 %
Biological Activity
Active
Catalog No. ABIN7884590
$297.95
Plus shipping costs $50.00
5 μg
Shipping to: United States
Delivery in 10 to 15 Business Days
Protein
  • WB (Western Blotting: Listed application)
Origin
Human
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Purity
>98 %
Biological Activity
Active
Catalog No. ABIN7884589
$297.95
Plus shipping costs $50.00
5 μg
Shipping to: United States
Delivery in 10 to 15 Business Days
Protein
  • Imm (Immunogen: Listed application)
Origin
Mouse
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Purity
> 90 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7669868
$1,902.46
Plus shipping costs $50.00
500 μg
Shipping to: United States
Delivery in 11 to 15 Business Days
Protein
  • Imm (Immunogen: Listed application)
Origin
Mouse
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Purity
> 90 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7669867
$1,902.46
Plus shipping costs $50.00
500 μg
Shipping to: United States
Delivery in 11 to 15 Business Days
Protein
  • AP (Affinity Purification: Listed application)
  • Func (Functional Studies: Listed application)
  • ScA (Screening Assay: Listed application)
Origin
Human
Host
Wheat germ
Protein Type
Recombinant
Catalog No. ABIN1330586
$799.44
Plus shipping costs $50.00, if applicable $20.00 dry ice
10 μg
Shipping to: United States
Delivery in 11 to 14 Business Days
Protein
  • CC (Cell Culture: Listed application)
Origin
Mouse
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Purity
> 98 % as determined by reducing SDS-PAGE.
Biological Activity
Active
Catalog No. ABIN7669866
$307.73
Plus shipping costs $50.00
20 μg
Shipping to: United States
Delivery in 11 to 15 Business Days

Latest Publications for our TRAIL Proteins

Borbone, De Rosa, Siciliano, Altucci, Croce, Fusco: "Up-regulation of miR-146b and down-regulation of miR-200b contribute to the cytotoxic effect of histone deacetylase inhibitors on ras-transformed thyroid cells." in: The Journal of clinical endocrinology and metabolism, Vol. 98, Issue 6, pp. E1031-40, (2013) (PubMed).

Pitti, Marsters, Ruppert, Donahue, Moore, Ashkenazi: "Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family." in: The Journal of biological chemistry, Vol. 271, Issue 22, pp. 12687-90, (1996) (PubMed).

Aliases for TRAIL Proteins

TNF superfamily member 10 (TNFSF10) Proteins
tumor necrosis factor (ligand) superfamily, member 10 (Tnfsf10) Proteins
TNF superfamily member 10 (Tnfsf10) Proteins
tumor necrosis factor superfamily member 10 (TNFSF10) Proteins
TNF superfamily member 10 S homeolog (tnfsf10.S) Proteins
TNF superfamily member 10 (tnfsf10) Proteins
A330042I21Rik Proteins
AI448571 Proteins
Apo-2L Proteins
APO-2L Proteins
apo-2l Proteins
APO2L Proteins
apo2l Proteins
CD253 Proteins
cd253 Proteins
Ly81 Proteins
TL2 Proteins
tl2 Proteins
tnfsf10l2 Proteins
TNLG6A Proteins
TRAIL Proteins
Trail Proteins
trail Proteins
trail1 Proteins
xtrail1 Proteins
zgc:92320 Proteins
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