Browse our MAL Proteins (MAL)

Full name:
Myelin and Lymphocyte Protein, T Cell Differentiation Protein Proteins (MAL)
On www.antibodies-online.com are 6 Myelin and Lymphocyte Protein, T Cell Differentiation Protein (MAL) Proteins from 3 different suppliers available. Additionally we are shipping MAL Antibodies (61) and MAL Kits (5) and many more products for this protein. A total of 74 MAL products are currently listed.
Synonyms:
mal, MALGENE, Mpv17, Vip17
list all proteins Gene Name GeneID UniProt
MAL 4118 P21145
MAL 17153 O09198
Rat MAL MAL 25263 Q64349

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MAL Proteins (MAL) by Origin

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More Proteins for MAL Interaction Partners

Human Myelin and Lymphocyte Protein, T Cell Differentiation Protein (MAL) interaction partners

  1. Here the authors show that MAL TIR domains spontaneously and reversibly form filaments in vitro. They also form cofilaments with TLR4 (show TLR4 Proteins) TIR domains and induce formation of MyD88 (show MYD88 Proteins) assemblies.

  2. MAL and TMEM220 were specifically methylated and were down-regulated in human gastric cancer.

  3. Results show that MAl protein (show Mall Proteins) binds to and regulates MYD88 (show MYD88 Proteins).

  4. This study revealed that Merkel cell polyomavirus -negative Merkel cell carcinomas significantly expressed higher CADM1 and lower MAL than Merkel cell polyomavirus -positive Merkel cell carcinomas

  5. CADM1/MAL methylation increases with severity of cervical intraepithelial neoplasia

  6. Hypermethylation of the selected markers (MAL, PRIMA1 (show PRIMA1 Proteins), PTGDR (show PTGDR Proteins) and SFRP1 (show SFRP1 Proteins)) can result in reduced gene expression and may contribute to the formation of colorectal cancer.

  7. Data suggest that expression of MAL in cells confers both ETX (Clostridium perfringens epsilon-toxin) binding and susceptibility to ETX-mediated cell death; cells expressing rat MAL are 100 times more sensitive to ETX than cells expressing human MAL.

  8. The use of CADM1, MAL, and MIR124-2 as biomarkers for full molecular screening in HIV infected women who are also positive for human papillomavirus.

  9. MAL is a critical element of the machinery for exosome secretion and may constitute a target for modulating exosome secretion by human T cells.

  10. MAL hypermethylation is associated with esophageal carcinoma progression.

Mouse (Murine) Myelin and Lymphocyte Protein, T Cell Differentiation Protein (MAL) interaction partners

  1. Expression of the developmentally regulated proteolipid MAL is required for the cytotoxic effect of Clostridium perfringens Epsilon Toxin.

  2. MAL (show TIRAP Proteins) overexpression leads to reduced expression of Mpz and p75NTR (show NGFR Proteins), despite functional pathways and normal expression of genes important for Schwann cell differentiation.

  3. the exclusion of MAL from the expanding 2D crystals of uroplakins explains the selective association of MAL with the hinge areas in the uroplakin-delivering fusiform vesicles, as well as at the apical surface

  4. Phagosomal retention of Francisella tularensis results in TIRAP/Mal (show TIRAP Proteins)-independent TLR2 signaling.

  5. The specific reduction and mistargeting of MAL protein (show Mall Proteins) as a reaction to sulfatide overload may contribute to the pathogenic mechanisms in metachromatic leukodystrophy.

  6. Our results demonstrate a critical role for MAL in the maintenance of central nervous system paranodes, likely by controlling the trafficking and/or sorting of NF155 and other membrane components in oligodendrocytes.

  7. Our results suggest a functional role for MAL in peripheral myelination by influencing the expression of membrane components that mediate axon-glia interaction during ensheathment and myelin wrapping.

Cow (Bovine) Myelin and Lymphocyte Protein, T Cell Differentiation Protein (MAL) interaction partners

  1. SYP is an hexameric MAL-domain channel protein.

MAL Protein Profile

Protein Summary

The protein encoded by this gene is a highly hydrophobic integral membrane protein belonging to the MAL family of proteolipids. The protein has been localized to the endoplasmic reticulum of T-cells and is a candidate linker protein in T-cell signal transduction. In addition, this proteolipid is localized in compact myelin of cells in the nervous system and has been implicated in myelin biogenesis and/or function. The protein plays a role in the formation, stabilization and maintenance of glycosphingolipid-enriched membrane microdomains. Down-regulation of this gene has been associated with a variety of human epithelial malignancies. Alternative splicing produces four transcript variants which vary from each other by the presence or absence of alternatively spliced exons 2 and 3.

Alternative names and synonyms associated with MAL

  • mal, T-cell differentiation protein (MAL)
  • myelin and lymphocyte protein, T cell differentiation protein (Mal)
  • myelin and lymphocyte protein (mal)
  • Myelin and lymphocyte protein (mal)
  • mal, T-cell differentiation protein (Mal)
  • mal protein
  • MALGENE protein
  • Mpv17 protein
  • Vip17 protein

Protein level used designations for MAL

T-lymphocyte maturation-associated protein , myelin and lymphocyte protein , myelin and lymphocyte protein, T-cell differentiation protein , Myelin and lymphocyte protein , 17 kDa myelin vesicular protein , MVP17 , NS 3 , VIP17 proteolipid , VIP17/MAL proteolipid

GENE ID SPECIES
4118 Homo sapiens
17153 Mus musculus
510077 Bos taurus
100135389 Xenopus (Silurana) tropicalis
100196291 Salmo salar
25263 Rattus norvegicus
403933 Canis lupus familiaris
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