Browse our Solute Carrier Family 37 (Glucose-6-Phosphate Transporter), Member 4 Proteins (SLC37A4)

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Solute Carrier Family 37 (Glucose-6-Phosphate Transporter), Member 4 Proteins (SLC37A4)
On www.antibodies-online.com are 3 Solute Carrier Family 37 (Glucose-6-Phosphate Transporter), Member 4 (SLC37A4) Proteins from 2 different suppliers available. Additionally we are shipping Solute Carrier Family 37 (Glucose-6-Phosphate Transporter), Member 4 Antibodies (32) and many more products for this protein. A total of 40 Solute Carrier Family 37 (Glucose-6-Phosphate Transporter), Member 4 products are currently listed.
Synonyms:
G6PC, G6PT, G6pt1, G6PT2, G6PT3, GSD-1b, GSD1b, GSD1c, GSD1d, mG6PT, MGC68695, MGC97640, pro0685, TRG-19, TRG19
list all proteins Gene Name GeneID UniProt
SLC37A4 2542 O43826
Mouse SLC37A4 SLC37A4 14385  
Rat SLC37A4 SLC37A4 29573  

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Solute Carrier Family 37 (Glucose-6-Phosphate Transporter), Member 4 Proteins (SLC37A4) by Origin

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More Proteins for Solute Carrier Family 37 (Glucose-6-Phosphate Transporter), Member 4 Interaction Partners

Human Solute Carrier Family 37 (Glucose-6-Phosphate Transporter), Member 4 (SLC37A4) interaction partners

  1. The most common mutation of SLC37A4 genes identified in Korean patients was c.443C>T (p.Ala148Val), accounting for 55.6% (5/9 patients) of all GSD Ib patients and 38.9% of the tested alleles

  2. Post-translational regulation of the glucose-6-phosphatase (show G6PC Proteins) complex by cyclic AMP (show APRT Proteins) is a crucial determinant of endogenous glucose production and is controlled by the glucose-6-phosphate transporter.

  3. Data suggest that G6PT (show G6PC Proteins) modulates autophagy independent of its transport activity; G6PT (show G6PC Proteins) appears to up-regulate autophagy via inactivation of mTORC1; knockdown of G6PT (show G6PC Proteins) expression activates mTORC1 (mechanistic target of rapamycin (show FRAP1 Proteins) complex 1) activity.

  4. Five SLC37A4 gene mutations were detected in 7 (25%) of the 28 children

  5. A total of 11 SLC37A4 gene mutations were identified in 15 families of the mainland of China. The frequent mutations are p.Pro191Leu, p.Gly149Glu and c.870 + 5G > A.

  6. Our results suggest that in Sardinia, Glycogen (show GYS1 Proteins) storage disease Ib is caused by only one mutational event in the G6PT (show G6PC Proteins) gene, further suggesting that Sardinia is a founder population.

  7. operates by a similar antiport mechanism as its E. coli homologue, namely, the substrate binds at the N- and C-terminal domain interface and is then transported across the membrane via a rocker (show CACNA1A Proteins)-switch type of movement of the two domains

  8. mutational analysis of G6PT1 in type I glycogen (show GYS1 Proteins) storage disease

  9. Overexpression of recombinant glucose-6-phosphate translocase rescued the cells from curcumin-induced cell death [ glucose-6-phosphate translocase]

  10. A novel G6PT1 promoter polymorphism, 259C --> T was found; the - 259*T allele frequency was greater in term SIDS (show IDS Proteins) infants than in term control infants and preterm SIDS (show IDS Proteins) infants

Mouse (Murine) Solute Carrier Family 37 (Glucose-6-Phosphate Transporter), Member 4 (SLC37A4) interaction partners

  1. Specific reduction of G6PT (show G6PC Proteins) may contribute to downregulation of hepatic 11beta-HSD1 (show HSD11B1 Proteins) in diabetic mice.

  2. hepatic G6PT (show G6PC Proteins) functions as an uniporter

  3. Findings suggest that increased hepatic H6PDH and G6PT (show G6PC Proteins) production contribute to 11beta-HSD1 (show HSD11B1 Proteins) upregulation of local glucocorticoid action that may be related to the development of type 2 diabetes.

  4. Evidence for the expression of G6PT1 in pancreatic islets.

  5. there is an MT1-MMP (show MMP14 Proteins)/G6PT (show G6PC Proteins) signaling axis that regulates BMSC survival, ECM (show MMRN1 Proteins) degradation, and mobilization

  6. Data suggest that G6PT (show G6PC Proteins) may account for the metabolic flexibility that enables MSCs to survive under conditions characterized by hypoxia and could be specifically targeted within developing tumors.

Solute Carrier Family 37 (Glucose-6-Phosphate Transporter), Member 4 (SLC37A4) Protein Profile

Protein Summary

This gene regulates glucose-6-phosphate transport from the cytoplasm to the lumen of the endoplasmic reticulum, in order to maintain glucose homeostasis. It also plays a role in ATP-mediated calcium sequestration in the lumen of the endoplasmic reticulum. Mutations in this gene have been associated with various forms of glycogen storage disease. Alternative splicing in this gene results in multiple transcript variants.

Alternative names and synonyms associated with Solute Carrier Family 37 (Glucose-6-Phosphate Transporter), Member 4 (SLC37A4)

  • solute carrier family 37 (glucose-6-phosphate transporter), member 4 (SLC37A4)
  • solute carrier family 37 (glucose-6-phosphate transporter), member 4 (slc37a4)
  • solute carrier family 37 (glucose-6-phosphate transporter), member 4 (LOC785602)
  • solute carrier family 37 (glucose-6-phosphate transporter), member 4 (Slc37a4)
  • G6PC protein
  • G6PT protein
  • G6pt1 protein
  • G6PT2 protein
  • G6PT3 protein
  • GSD-1b protein
  • GSD1b protein
  • GSD1c protein
  • GSD1d protein
  • mG6PT protein
  • MGC68695 protein
  • MGC97640 protein
  • pro0685 protein
  • TRG-19 protein
  • TRG19 protein

Protein level used designations for SLC37A4

glucose-6-phosphate translocase , glucose-6-phosphatase, catalytic subunit , solute carrier family 37 (glucose-6-phosphate transporter), member 4 , solute carrier family 37 (glycerol-6-phosphate transporter), member 4 , glucose-6-phosphate translocase-like , glucose-5-phosphate transporter , glucose-6-phosphatase, transport (glucose) protein 3 , glucose-6-phosphatase, transport (glucose-6-phosphate) protein 1 , glucose-6-phosphatase, transport (phosphate/pyrophosphate) protein 2 , microsomal glucose-6-phosphate transporter , solute carrier family 37 member 4 , transformation-related gene 19 protein , glucose 6-phosphate transporter , glucose-6-phosphatase, transport protein 1 , transporter , glucose-6-phosphatase transport protein 1

GENE ID SPECIES
702269 Macaca mulatta
398908 Xenopus laevis
419789 Gallus gallus
451599 Pan troglodytes
550110 Xenopus (Silurana) tropicalis
785602 Bos taurus
100171575 Pongo abelii
100332703 Danio rerio
100357958 Oryctolagus cuniculus
100411680 Callithrix jacchus
100464788 Ailuropoda melanoleuca
100557460 Anolis carolinensis
2542 Homo sapiens
100516688 Sus scrofa
506423 Bos taurus
14385 Mus musculus
29573 Rattus norvegicus
489375 Canis lupus familiaris
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