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The children having both ACTN3 (show ACTN3 ELISA Kits) RR or RX genotype and ACE (show ACE ELISA Kits) DD genotype showed high systolic blood pressure and low blood HDL (show HSD11B1 ELISA Kits) cholesterol level, which may be considered a high-risk in metabolic syndrome.
This study has thus revealed a novel nuclear complex of F-actin, DRR1 (show FAM107A ELISA Kits) and COMMD1 (show COMMD1 ELISA Kits) that is involved in NF-kappaB (show NFKB1 ELISA Kits) degradation and cell cycle suppression in neuroblastoma (show ARHGEF16 ELISA Kits) cells.
These results provide new insights into the regulation of SK2 (show KCNN2 ELISA Kits) channel trafficking by the cytoskeletal proteins FLNA (show FLNA ELISA Kits) and alpha-actinin2, involving distinct recycling pathways
The RR genotype of ACTN3 (show ACTN3 ELISA Kits) R577X in the general Japanese population showed lower flexibility compared to the RX and XX genotypes.
p16(INK4a) expression in MCF7 breast cancer cells leads to increased cell size, weakened intercellular adhesion and cortical re-distribution of cytoskeletal F-actin.
the interaction between GNE (show GNE ELISA Kits) and alpha-actinin 1 (show ACTN1 ELISA Kits) and alpha-actinin 2 (show ACTN2 ELISA Kits) occur at different sites in the alpha-actinin (show ACTN1 ELISA Kits) molecules and that for alpha-actinin 2 (show ACTN2 ELISA Kits) the interaction site is located at the C-terminus of the protein.
our data showed a virtual absence of the variant (K) allele in MSTN (show MSTN ELISA Kits) rs1805086 in Japanese population, and no differences in allele/genotype frequencies in ACTN3 (show ACTN3 ELISA Kits) rs1815739 among centenarians and healthy controls of this country.
Results indicate that the posthemorrhagic shock mesenteric lymph in vitro increases the cellular permeability of human umbilical vein endothelial cells through suppression of F-actin and VE-cadherin (show CDH5 ELISA Kits).
These findings provide the basis for further functional investigations of the ITSN/CR16 complex that may play an important role in actin remodeling and cellular invasion.
The elite soccer players showed a tendency to a prevalence of ACTN3 (show ACTN3 ELISA Kits) RR and ACE (show ACE ELISA Kits) DD genotypes both independently and in co-occurrence, in comparison with a general population.
This gene encodes a member of the alpha-actin binding protein gene family. The encoded protein is primarily expressed in skeletal muscle and functions as a structural component of sarcomeric Z line. This protein is involved in crosslinking actin containing thin filaments. An allelic polymorphism in this gene results in both coding and non-coding variants. The reference genome contains the non-coding allele. The non-functional allele of this gene is associated with elite athlete status.
F-actin cross-linking protein
, alpha-actinin skeletal muscle
, non-muscle alpha-actinin 4