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Human CSF3 Primary Antibody for ELISA - ABIN414378
Wu, Guo, Yao, Miao, Liang, Liu, Wang, Zhang: The Transcriptional Foundations of Sp110-mediated Macrophage (RAW264.7) Resistance to Mycobacterium tuberculosis H37Ra. in Scientific reports 2016
data provide novel information about the regulation of neutrophil migration in zebrafish, positioning Gcsf-Chr19 as a key signal during the course of an inflammatory process triggered by severe damage
Data indicate that Gcsf is required for the specification and proliferation of hematopoietic stem cells, suggesting that Gcsf represents an ancestral cytokine responsible for the broad support of hematopoietic stem and progenitor cells (HSPCs).
SB203580 increases G-CSF expression in macrophages by increasing the stability of G-CSF mRNA via its 3'UTR (show UTS2R ELISA Kits), and the effect was not due to its inhibition of p38 MAPK (show MAPK14 ELISA Kits) activity.
Results suggested that G-CSF plays an important role in preventing colitis, likely through populating immune regulatory macrophages in the intestine.
findings provide convincing evidence that monophosphoryl lipid A-induced G-CSF facilitates early expansion, mobilization, and recruitment of neutrophils to the site of infection after burn injury
Overexpression of VEGF (show VEGFA ELISA Kits) may compensate for the G-CSF deficit through preservation of cellular components, including blood vessels, in the postinfarction heart.
G-CSF supports long-term muscle regeneration in mouse models of muscular dystrophy.
constitutive activation of the NF-kappaB (show NFKB1 ELISA Kits) pathway in CAIX (show CA9 ELISA Kits)-depleted cells restored G-CSF secretion
Exposure of Sca-1(+) cells to G-CSF in the culture medium for 72 h induced time-dependent but self-limiting cell cycle acceleration with a restricted effect on the CSC proliferation.
these results suggest that the G-CSF pathway regulates the production of autoantibodies in murine models of lupus.
G-CSF acts in a cell intrinsic manner to expand multipotent progenitors to increase production of tumor-derived Ly6G+ neutrophils.
Endothelial cell(EC)-intrinsic MYD88 (show MYD88 ELISA Kits) signaling and subsequent G-CSF production by ECs is required for myeloid progenitor lineage skewing toward granulocyte-macrophage progenitors, increased colony-forming unit granulocyte activity.
These results suggest that G-CSF could decrease the Th1 (show TH1L ELISA Kits)/Th2 ratio in the context of immune thrombocytopenic purpura, and elucidate the direct and indirect immunomodulatory mechanisms underlying G-CSF functions in Th1 (show TH1L ELISA Kits)/Th2 cells.
GCSF impairs CD8 (show CD8A ELISA Kits)(+) T cell functionality by interfering with central activation elements.
High expression of G-CSF is associated with Tongue squamous cell carcinoma.
this study shows that haplotypes consisting of single nucleotide polymorphisms harboring PSMD3 (show PSMD3 ELISA Kits), CSF3 and MED24 (show MED22 ELISA Kits) genes are associated with asthma in Slovenian patients
Cancer cells can produce IL-18 (show IL18 ELISA Kits), which is involved in the process of angiogenesis, stimulates invasion and metastasis. Decrease in SIPA for the production of IL-6 (show IL6 ELISA Kits) and GCSF by peripheral blood cells could serve as an indicator of malignant progression in invasive ductal breast carcinoma.
G-CSF showed favorable effects only on the migration of HUVECs, and no direct influence was found on Osteoblasts.
tumor G-CSF expression is an indicator of an extremely poor prognosis in cervical cancer patients that are treated with chemotherapy.
G-CSF stimulates beta1 integrin expression and Swan (show RBM12 ELISA Kits) 71 cell migration by activating PI3K (show PIK3CA ELISA Kits) and MAPK (show MAPK1 ELISA Kits) signaling pathways.
these data suggest that G-CSF may contribute to tumor growth and decrease the antitumor effect of radiotherapy, possibly by promoting vascularization in cancer lesions.
in vitro chemotaxis assays and an in vivo transplantation model for chemoattraction confirmed that UCX((R)) are chemotactic to CD34 (show CD34 ELISA Kits)(-)/CD45 (show PTPRC ELISA Kits)(-) BM-MSCs via a cell-specific mobilization mechanism mediated by G-CSF.
Data suggest granulocyte-colony stimulating factor (G-CSF) as a possible candidate for agents in which neutrophils can provide protection.
The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes. The active protein is found extracellularly. Alternatively spliced transcript variants have been described for this gene.
colony stimulating factor 3 (granulocyte)
, granulocyte colony-stimulating factor
, granulocyte colony stimulating factor
, Granulocyte colony-stimulating factor