Browse our C1R (C1R) ELISA Kits

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Complement Component 1, R Subcomponent ELISA Kits (C1R)
On are 29 Complement Component 1, R Subcomponent (C1R) ELISA Kits from 10 different suppliers available. Additionally we are shipping C1R Antibodies (72) and C1R Proteins (5) and many more products for this protein. A total of 111 C1R products are currently listed.
C1R, c1rl, MGC84776, MGC127774
list all ELISA KIts Gene Name GeneID UniProt
C1R 715 P00736
C1R 312705  

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More ELISA Kits for C1R Interaction Partners

Human Complement Component 1, R Subcomponent (C1R) interaction partners

  1. We identified a novel, homozygous, loss-of-function mutation (p.Pro445Leufs*11) in the C1R gene. Using the Sanger method of DNA sequencing in 14 family members, we confirmed the presence of the mutation in 4 patients with early-onset systemic lupus erythematosus and in an asymptomatic 9-year-old girl. Complement levels were low in sera from patients with truncated C1r protein.

  2. Periodontal Ehlers-Danlos Syndrome in at least the great majority of cases results from specific classes of heterozygous mutations in C1R and C1S (show C1S ELISA Kits).

  3. We confirmed increased levels of C1R and VTN (show VTN ELISA Kits) in sera from patients with Joint hypermobility syndrome by western blot analyses

  4. C1q exists as the C1 complex (C1qC1r2C1s2), and C1q binding to ligands activates the C1r/C1s (show C1S ELISA Kits) proteases. Incubation of nucleoli with C1 caused degradation of the nucleolar proteins nucleolin (show NCL ELISA Kits) and nucleophosmin 1 (show NPM1 ELISA Kits). T

  5. C1r specificity is well suited to its cleavage targets and that efficient cleavage of C1s (show C1S ELISA Kits) is achieved through both active site and exosite contributions.

  6. Analysis of its interaction properties by surface plasmon resonance shows that rC1q retains the ability of serum C1q to associate with the C1s (show C1S ELISA Kits)-C1r-C1r-C1s (show C1S ELISA Kits) tetramer, to recognize physiological C1q ligands such as IgG and pentraxin 3 (show PTX3 ELISA Kits)

  7. a structural rearrangement as a switch between functional states of human C1r

  8. These results provide further structural insights into the architecture of the C1 complex, and the interactions between C1r and C1s (show C1S ELISA Kits).

  9. The modular C1r protein is the first protease activated in the classical complement pathway, a key component of innate immunity.

  10. Detailed mapping of C1q post-translational modifications and insights into the C1r/C1s (show C1S ELISA Kits) binding sites.

C1R Antigen Profile

Antigen Summary

C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system.

Alternative names and synonyms associated with C1R

  • complement component 1, r subcomponent (C1R) Elisa Kit
  • complement component 1, r subcomponent (C1r) Elisa Kit
  • complement component 1, r subcomponent (c1r) Elisa Kit
  • C1R Elisa Kit
  • c1rl Elisa Kit
  • MGC84776 Elisa Kit
  • MGC127774 Elisa Kit

Protein level used designations for C1R

complement C1r subcomponent , complement C1r , complement component 1, r subcomponent , complement component 1 subcomponent r

715 Homo sapiens
445464 Sus scrofa
312705 Rattus norvegicus
418295 Gallus gallus
444745 Xenopus laevis
466939 Pan troglodytes
477707 Canis lupus familiaris
511581 Bos taurus
613057 Xenopus (Silurana) tropicalis
100549554 Meleagris gallopavo
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