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Browse our APLF Proteins (APLF)

Full name:
Aprataxin and PNKP Like Factor Proteins (APLF)
On www.antibodies-online.com are 5 Aprataxin and PNKP Like Factor (APLF) Proteins from 3 different suppliers available. Additionally we are shipping APLF Antibodies (35) and many more products for this protein. A total of 42 APLF products are currently listed.
Synonyms:
2010301N04Rik, AI452191, APFL, APLF, C2orf13, DKFZp459J1223, PALF, RGD1565557, Xip1
list all proteins Gene Name GeneID UniProt
APLF 200558 Q8IW19
APLF 72103 Q9D842
Rat APLF APLF 500247  

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APLF Proteins (APLF) by Origin

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More Proteins for APLF Interaction Partners

Human Aprataxin and PNKP Like Factor (APLF) interaction partners

  1. These data suggest functional requirements for Ku and XRCC4 (show XRCC4 Proteins) in APLF-dependent NHEJ and a unique role for Ku as a factor required to facilitate the nuclear retention of APLF.

  2. APLF promotes the assembly and activity of multi-protein Ku-DNA complexes containing all of the Non-homologous end joining (NHEJ) factors required for DNA ligation.

  3. Polynucleotide kinase and aprataxin-like (show APTX Proteins) forkhead-associated protein (PALF) acts as both a single-stranded DNA endonuclease and a single-stranded DNA 3' exonuclease (show EXO1 Proteins) and can participate in DNA end joining in a biochemical system.

  4. only a positive association (OR=1.58, 95% CI 1.05-2.46, P=0.027) was obtained for XRCC1 (show XRCC1 Proteins) (Arg280His

  5. APLF has a role in chromosomal DNA double-strand break repair.

  6. The poly(ADP-ribose)-regulated protein APLF as a DNA-damage-specific histone chaperone.

  7. The authors present solution structures of the two poly(ADP-ribose)-binding zinc finger modules of aprataxin and PNK-like factor (APLF), revealing a novel type of zinc finger.

  8. These data identify APLF as a novel component of the cellular response to DNA strand breaks in human cells.

  9. PALF is novel human AP endonuclease with conserved zinc-finger-like motifs involved in DNA strand break responses.

  10. APLF is an ATM (show ATM Proteins) target that is involved in nonhomologous end-joining and facilitates double-strand break repair, likely via interactions with Ku and XRCC4 (show XRCC4 Proteins)-DNA ligase IV (show LIG4 Proteins).

Mouse (Murine) Aprataxin and PNKP Like Factor (APLF) interaction partners

  1. APLF has a role in chromosomal DNA double-strand break repair.

APLF Protein Profile

Protein Summary

C2ORF13 is a component of the cellular response to chromosomal DNA single- and double-strand breaks (Iles et al., 2007

Alternative names and synonyms associated with APLF

  • aprataxin and PNKP like factor (APLF)
  • aprataxin and PNKP like factor (aplf)
  • aprataxin and PNKP like factor (LOC100342776)
  • aprataxin and PNKP like factor (Aplf)
  • 2010301N04Rik protein
  • AI452191 protein
  • APFL protein
  • APLF protein
  • C2orf13 protein
  • DKFZp459J1223 protein
  • PALF protein
  • RGD1565557 protein
  • Xip1 protein

Protein level used designations for APLF

aprataxin and PNKP like factor , aprataxin and PNK-like factor-like , PNK and APTX-like FHA domain-containing protein , PNK and APTX-like FHA protein , XRCC1-interacting protein 1 , aprataxin and PNK-like factor , aprataxin- and PNK-like factor , apurinic-apyrimidinic endonuclease APLF

GENE ID SPECIES
481405 Canis lupus familiaris
705875 Macaca mulatta
100061683 Equus caballus
100127823 Xenopus (Silurana) tropicalis
100173335 Pongo abelii
100342776 Oryctolagus cuniculus
100389227 Callithrix jacchus
100595038 Nomascus leucogenys
200558 Homo sapiens
72103 Mus musculus
507989 Bos taurus
500247 Rattus norvegicus
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