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Browse our anti-Family with Sequence Similarity 175, Member A (FAM175A) Antibodies

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anti-Family with Sequence Similarity 175, Member A Antibodies (FAM175A)
On www.antibodies-online.com are 47 Family with Sequence Similarity 175, Member A (FAM175A) Antibodies from 15 different suppliers available. Additionally we are shipping Family with Sequence Similarity 175, Member A Proteins (9) and Family with Sequence Similarity 175, Member A Kits (1) and many more products for this protein. A total of 63 Family with Sequence Similarity 175, Member A products are currently listed.
Synonyms:
3830405G04Rik, 5630400M01Rik, ABRA1, AI506069, AL024423, AV118690, Ccdc98, fam175a, RGD1305287, zgc:103522
list all antibodies Gene Name GeneID UniProt
FAM175A 84142 Q6UWZ7
FAM175A 70681 Q8BPZ8
FAM175A 289468 Q5I0F1

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Top referenced anti-Family with Sequence Similarity 175, Member A Antibodies

  1. Human Polyclonal FAM175A Primary Antibody for IHC, ELISA - ABIN1002067 : Kim, Huang, Chen: CCDC98 is a BRCA1-BRCT domain-binding protein involved in the DNA damage response. in Nature structural & molecular biology 2007 (PubMed)
    Show all 3 references for ABIN1002067

  2. Human Monoclonal FAM175A Primary Antibody for FACS, IP - ABIN1302443 : Wang, Elledge: Ubc13/Rnf8 ubiquitin ligases control foci formation of the Rap80/Abraxas/Brca1/Brcc36 complex in response to DNA damage. in Proceedings of the National Academy of Sciences of the United States of America 2007 (PubMed)
    Show all 3 references for ABIN1302443

More Antibodies against Family with Sequence Similarity 175, Member A Interaction Partners

Human Family with Sequence Similarity 175, Member A (FAM175A) interaction partners

  1. Demonstrate a mechanism involving IR-induced phosphorylation and dimerization of the BRCT/Abraxas complex for regulating Abraxas-mediated recruitment of BRCA1 in response to IR.

  2. Abraxas and RAP80 (show UIMC1 Antibodies) were required for DNA damage resistance, G(2)-M checkpoint control, and DNA repair.

  3. CCDC98 is a BRCA1 binding partner that mediates BRCA1 function in response to DNA damage.

  4. CCDC98 is a mediator of BRCA1 function involved in the mammalian DNA damage response.

  5. the human Ubc13 (show UBE2N Antibodies)/Rnf8 (show RNF8 Antibodies) ubiquitin ligases control foci formation of the Rap80 (show UIMC1 Antibodies)/Abraxas/Brca1/Brcc36 (show BRCC3 Antibodies) complex in response to DNA damage

  6. Mutational analysis in 168 multiple-case breast/ovarian cancer families, negative for mutations in BRCA1 or BRCA2 (show BRCA2 Antibodies), suggests that CCDC98 does not play an important role as a high penetrance breast cancer susceptibility gene.

  7. it seems unlikely that moderate to highly penetrant alleles of either RAP80 (show UIMC1 Antibodies) or Abraxas, confer a significantly high relative risk of breast cancer.

  8. examined RAP80 (show UIMC1 Antibodies) and Abraxas expression and their effect on treatment outcome in non-small-cell lung cancer

Family with Sequence Similarity 175, Member A (FAM175A) Antigen Profile

Antigen Summary

Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the brca1-bard1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX. In the BRCA1-A complex, it acts as a central scaffold protein that assembles the various components of the BRCA1-A complex and mediates the recruitment of brca1 (By similarity).

Alternative names and synonyms associated with Family with Sequence Similarity 175, Member A (FAM175A)

  • coiled-coil domain containing 98 (CCDC98) antibody
  • Coiled-coil domain-containing protein 98 (ccd98) antibody
  • family with sequence similarity 175, member A (FAM175A) antibody
  • family with sequence similarity 175, member A (Fam175a) antibody
  • family with sequence similarity 175, member A (fam175a) antibody
  • 3830405G04Rik antibody
  • 5630400M01Rik antibody
  • ABRA1 antibody
  • AI506069 antibody
  • AL024423 antibody
  • AV118690 antibody
  • Ccdc98 antibody
  • fam175a antibody
  • RGD1305287 antibody
  • zgc:103522 antibody

Protein level used designations for FAM175A

coiled-coil domain containing 98 , BRCA1-A complex subunit Abraxas , Protein FAM175A , abraxas protein , coiled-coil domain-containing protein 98

GENE ID SPECIES
461205 Pan troglodytes
100194936 Salmo salar
84142 Homo sapiens
70681 Mus musculus
289468 Rattus norvegicus
504796 Bos taurus
422608 Gallus gallus
478459 Canis lupus familiaris
449820 Danio rerio
443765 Xenopus laevis
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