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Browse our ALDH1A1 Proteins (ALDH1A1)

Full name:
Aldehyde Dehydrogenase 1 Family, Member A1 Proteins (ALDH1A1)
On are 29 Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) Proteins from 11 different suppliers available. Additionally we are shipping ALDH1A1 Antibodies (240) and ALDH1A1 Kits (33) and many more products for this protein. A total of 316 ALDH1A1 products are currently listed.
Ahd-2, Ahd2, AL1A1, ALDC, ALDDH, ALDH-E1, Aldh1, ALDH1A1, Aldh1a2, Aldh2, ALDH11, E1, GGADHR, PUMB1, Raldh1
list all proteins Gene Name GeneID UniProt
ALDH1A1 216 P00352
ALDH1A1 24188 P51647
ALDH1A1 11668 P24549

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ALDH1A1 Proteins (ALDH1A1) by Origin

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Top referenced ALDH1A1 Proteins

  1. Human ALDH1A1 Protein expressed in Escherichia coli (E. coli) - ABIN666900 : Pereira, Rosenmann, Nylen, Kaufman, Pinsky, Wrogemann: The 56 kDa androgen binding protein is an aldehyde dehydrogenase. in Biochemical and biophysical research communications 1991 (PubMed)

  2. Human ALDH1A1 Protein expressed in Escherichia coli (E. coli) - ABIN2004256 : Hough, Piatigorsky: Preferential transcription of rabbit Aldh1a1 in the cornea: implication of hypoxia-related pathways. in Molecular and cellular biology 2004 (PubMed)

More Proteins for ALDH1A1 Interaction Partners

Human Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) interaction partners

  1. ALDH1A1 and IGFBP1 (show IGFBPI Proteins) are differentially overexpressed in CLM (show LAMB1 Proteins) and may play a dual role, functioning as both tumor suppressors and metastasis promoters in CRC (show CALR Proteins)

  2. CD44 (show CD44 Proteins)+/24- and ALDH1-positive rates in primary tumors differed according to intrinsic subtype. ER-positive patients with CD44 (show CD44 Proteins)+/24- tumors had significantly longer disease-free-survival than all other ER-positive patients

  3. ALDH1 positivity is associated with poor prognosis of cervical carcinoma, and may be an independent predictor of prognosis.

  4. High ALDH1A1 expression is associated with bladder cancer.

  5. Results indicate that ALDH1A1 is associated with cisplatin resistance in human lung adenocarcinoma cell line A549/DDP (show TIMM8A Proteins) cells, and that activation of the PI3K (show PIK3CA Proteins)/AKT (show AKT1 Proteins) signal pathway may be the responsible mechanism.

  6. We ascertained the presence of strong association between ALDH1A1 expression and both histological subtype & tumor grade of non-small cell lung cancers. We report a fascinating finding; ALDH1A1 heterogeneity within adenocarcinoma can be mapped to its histological patterns.

  7. Whole-tissue is better than TMA for the detection of ALDH1A1 nuclear staining in colorectal carcinoma patients, and nuclear expression is associated with a better outcome. Cytoplasmic expression is not a suitable prognostic marker of colorectal carcinoma.

  8. Data support a crucial role of Notch3 (show NOTCH3 Proteins) in the increase of stem-like property in NSCLC cells that might be associated with upregulation of ALDH1A1 and CD44 (show CD44 Proteins) and activation of autophagy.

  9. CD44 (show CD44 Proteins)(+)ALDH1(+)Ki-67 (show MKI67 Proteins)(-) tumor cells may favor distant metastasis; quiescence may have a crucial role for tumor progression, treatment resistance and metastatic ability of breast cancer stem cells

  10. Data suggest that posttreatment aldehyde dehydrogenase 1(ALDH1) and CD44 antigen (show CD44 Proteins) positivity might affect poor response to preoperative chemoradiotherapy (CRT (show SLC6A8 Proteins)).

Cow (Bovine) Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) interaction partners

  1. analysis of bioactivation of nitroglycerin by purified mitochondrial and cytosolic aldehyde dehydrogenases ALDH1 and ALDH2 (show ALDH2 Proteins)

Mouse (Murine) Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) interaction partners

  1. Data indicate involvement of non-POU domain-containing octamer-binding protein (NONO (show NONO Proteins))/paraspeckle protein component 1 (PSPC1 (show PSPC1 Proteins))-aldehyde dehydrogenase 1 (NONO (show NONO Proteins)/PSPC1 (show PSPC1 Proteins)-ALDH1A1) in the modulation of Sertoli cells (SCs (show TWIST1 Proteins)) response to mono-(2-ethylhexyl) phthalate (MEHP) challenge.

  2. In ovaries lacking ALDH1A1, the onset of germ cell meiosis is delayed.

  3. Dioxin receptor regulates aldehyde dehydrogenase to block melanoma tumorigenesis and metastasis

  4. these experiments reveal an evolutionarily conserved GABA synthesis pathway mediated by aldehyde dehydrogenase 1a1 (ALDH1a1).

  5. Respiratory tract epithelial cells express retinaldehyde dehydrogenase ALDH1A and enhance IgA production by stimulated B cells in the presence of vitamin A.

  6. Dkk-1 (show DKK1 Proteins) enhances resistance of osteosarcoma cells to stress by tipping balance of Wnt (show WNT2 Proteins) signaling in favor of the non-canonical Jun (show JUN Proteins)-mediated Wnt (show WNT2 Proteins) pathways. In turn, this results in transcriptional activation of ALDH1 through Jun (show JUN Proteins)-responsive promoter elements.

  7. Deletion of Aldh1a1 exacerbated alpha-synuclein-mediated DA neurodegeneration and alpha-synuclein aggregation, whereas Aldh1a1-null and control DA neurons were comparably susceptible to 1-methyl-4-phenylpyridinium-, glutamate (show GRIN1 Proteins)-, or camptothecin-induced cell death.

  8. Our findings indicated that increased expression of ALDH1A1 in nasopharyngeal carcinoma was associated with enhanced invasiveness in the nude mouse.

  9. PSMB8 (show PSMB8 Proteins), ALDH1A1, and HSPA4 (show HSPA4 Proteins) were identified to be located in ovarian tissues, to regulate 12 cellular pathways, and demonstrate age-dependent dynamic changes in expression profiling.

  10. beta-escin inhibits tobacco carcinogen-induced lung tumor formation by modulating ALDH1A1-positive cells and RhoA (show RHOA Proteins)/Rock signaling

ALDH1A1 Protein Profile

Protein Summary

The protein encoded by this gene belongs to the aldehyde dehydrogenase family. Aldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. There are two major aldehyde dehydrogenase isozymes in the liver, cytosolic and mitochondrial, which are encoded by distinct genes, and can be distinguished by their electrophoretic mobility, kinetic properties, and subcellular localization. This gene encodes the cytosolic isozyme. Studies in mice show that through its role in retinol metabolism, this gene may also be involved in the regulation of the metabolic responses to high-fat diet.

Alternative names and synonyms associated with ALDH1A1

  • aldehyde dehydrogenase 1 family, member A1 (ALDH1A1)
  • aldehyde dehydrogenase 1 family, member A1 (aldh1a1)
  • aldehyde dehydrogenase (aldH1)
  • aldehyde dehydrogenase family protein (aldh1)
  • NADP-dependent fatty aldehyde dehydrogenase (aldH1)
  • aldehyde dehydrogenase 1 family, member A1 (Aldh1a1)
  • aldehyde dehydrogenase 2 family (mitochondrial) (Aldh2)
  • aldehyde dehydrogenase family 1, subfamily A1 (Aldh1a1)
  • Ahd-2 protein
  • Ahd2 protein
  • AL1A1 protein
  • ALDC protein
  • ALDDH protein
  • ALDH-E1 protein
  • Aldh1 protein
  • ALDH1A1 protein
  • Aldh1a2 protein
  • Aldh2 protein
  • ALDH11 protein
  • E1 protein
  • GGADHR protein
  • PUMB1 protein
  • Raldh1 protein

Protein level used designations for ALDH1A1

aldehyde dehydrogenase 1A1 , retinal dehydrogenase 1 , aldehyde dehydrogenase 1 family, member A1 , aldehyde dehydrogenase class 1 , retinal dehydrogenase 1-like , aldehyde dehydrogenase , aldehyde dehydrogenase family protein , NADP-dependent fatty aldehyde dehydrogenase , ALDH class 1 , ALHDII , RALDH 1 , acetaldehyde dehydrogenase 1 , aldehyde dehydrogenase 1, soluble , aldehyde dehydrogenase, liver cytosolic , retinaldehyde dehydrogenase 1 , chromosome 1 GSS clone AHT1-34 , ALDH-E1 , aldehyde dehydrogenase 1, subfamily A1 , aldehyde dehydrogenase 2 , aldehyde dehydrogenase family 1 member A1 , aldehyde dehydrogenase family 1, member A1 , aldehyde dehydrogenase family 1, subfamily A1 , aldehyde dehydrogenase, cytosolic , ralDH1 , cytosolic aldehyde dehydrogenase , ALDH class 2 , ALDH-E2 , ALDH1 , aldehyde dehydrogenase 2, mitochondrial , aldehyde dehydrogenase, mitochondrial , mitochondrial aldehyde dehydrogenase , alcohol dehydrogenase family 1, subfamily A1 , alcohol dehydrogenase family 1, subfamily A2 , aldehyde dehydrogenase 1, liver cytosolic (class 1)

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5714098 Dinoroseobacter shibae DFL 12
5775460 Staphylococcus aureus subsp. aureus USA300_TCH1516
5953724 Halobacterium salinarum R1
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216 Homo sapiens
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443343 Ovis aries
29539 Rattus norvegicus
11668 Mus musculus
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