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Human FBLN3 ELISA Kit for Sandwich ELISA - ABIN421041
Pass, Levin, Harbut, Melamed, Chiriboga, Donington, Huflejt, Carbone, Chia, Goodglick, Goodman, Thornquist, Liu, de Perrot, Tsao, Goparaju: Fibulin-3 as a blood and effusion biomarker for pleural mesothelioma. in The New England journal of medicine 2012
Show all 11 Pubmed References
Results indicate that fibulin-3 serves as a pro-invasive factor in bladder cancer, which may be mediated through modulation of IGFBP5 (show IGFBP5 ELISA Kits) expression.
fibulin-3 confers a relatively high diagnostic efficacy and is acceptable to be an auxiliary biomarker to aid in malignant pleural mesothelioma identification.
FBLN-3 promoter region was highly methylated in some pancreatic cancer cell lines. FBLN-3 inhibited c-MET activation and expression and reduced cellular level of ALDH1 (show ALDH1A1 ELISA Kits).
Serum EFEMP1 is down-regulated and involved in the progression of Prostate Cancer. It may serve as a useful diagnostic biomarker, with better diagnostic accuracy than PSA in Prostate Cancer.
SMRP (show ABCC5 ELISA Kits) but not FBLN3 has a role in pleural effusions in in malignant pleural mesothelioma
EFEMP1 negatively modulates the migration ability in hepatocellular carcinoma. Reduction of EFEMP1 promotes the migration ability though increasing Matrix Metalloproteinase 2 (show MMP2 ELISA Kits) and Matrix Metalloproteinase 9 (show MMP9 ELISA Kits) expression via Extracellular Signal-Regulated MAP Kinase 1 (show MAPK3 ELISA Kits)/2 activity.
The EFEMP1 rs3791679 polymorphism influences glioma susceptibility in the Chinese Han population.
Extensive methylation of the EFEMP1 gene promoter can discriminate invasive from benign IPMNs with superior accuracy owing to their stepwise accumulation of tumor progression
The results of our study suggested an association between the EFEMP1 rs3791679 polymorphism and an elevated risk of glioma, especially in those with family history of glioma.
Median FBLN-3 concentrations were 12.96.
TWEAK (show TNFSF12 ELISA Kits) promotes migration and invasion in murine embryonic fibroblasts through a mechanism dependent on ERKs activation and Fibulin 3 down-regulation.
Mutant fibulin-3 causes proteoglycan (show Vcan ELISA Kits) accumulation, reduction of MMP-2 (show MMP2 ELISA Kits) and MMP-9 (show MMP9 ELISA Kits), but increase of TIMP-3 (show TIMP3 ELISA Kits), and impairs diffusion across Bruch's membrane.
Define the Efemp1-p27(Kip1 (show CDKN1B ELISA Kits)) axis as a potential marker module of PDAC cell sensitivity towards dual PI3K-mTOR (show FRAP1 ELISA Kits) inhibitors.
The Efemp1 knock-in mice reconstitute the most important histopathologic symptoms of both Malattia leventinese and age-related macular degeneration.
fibulin-3 plays an important role in maintaining the integrity of fascia connective tissues and regulates aging.
both fibulin-3 and -5 are important in maintaining pelvic organ support in mice.
Data suggest a role for fibulin-3 in tissue maintenance and regeneration in the adult olfactory pathway.
This gene encodes a member of the fibulin family of extracellular matrix glycoproteins. Like all members of this family, the encoded protein contains tandemly repeated epidermal growth factor-like repeats followed by a C-terminus fibulin-type domain. This gene is upregulated in malignant gliomas and may play a role in the aggressive nature of these tumors. Mutations in this gene are associated with Doyne honeycomb retinal dystrophy. Alternatively spliced transcript variants that encode the same protein have been described.
EGF-containing fibulin-like extracellular matrix protein 1
, extracellular protein S1-5
, epidermal growth factor-containing fibulin-like extracellular matrix protein 1