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Browse our Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 2 Proteins (STAM2)

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Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 2 Proteins (STAM2)
On www.antibodies-online.com are 6 Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 2 (STAM2) Proteins from 4 different suppliers available. Additionally we are shipping Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 2 Antibodies (83) and Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 2 Kits (3) and many more products for this protein. A total of 104 Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 2 products are currently listed.
Synonyms:
1200004O12Rik, 5730456G07Rik, BB145015, HBP, MGC52950, stam2, STAM2A, STAM2B, zgc:103628
list all proteins Gene Name GeneID UniProt
STAM2 10254 O75886
STAM2 56324 O88811
Rat STAM2 STAM2 311030 Q5XHY7

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Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 2 Proteins (STAM2) by Origin

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More Proteins for Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 2 Interaction Partners

Cow (Bovine) Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 2 (STAM2) interaction partners

  1. The G-102A polymorphism in STAM2 is significantly associated with withers height, heart girth, cannon circumference, chest width, and hip height in Wuchuan Black cattle

Human Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 2 (STAM2) interaction partners

  1. The VHS domain of STAM2 directs AMSH to cleave longer Lys63-linked ubiquitin chains

  2. homologous domain of human Bro1 (show HMGCR Proteins) domain-containing proteins, Alix (show PDCD6IP Proteins) and Brox, binds CHMP4B (show CHMP4A Proteins) but not STAM2, despite their high structural similarity

  3. arsenic, a carcinogenic metal, decreases cellular levels of SLBP (show SLBP Proteins) by inducing its proteasomal degradation and inhibiting SLBP (show SLBP Proteins) transcription via epigenetic mechanisms

  4. the S/G2 (show STRN3 Proteins) stable mutant form of SLBP (show SLBP Proteins) is degraded by proteasome in G1, indicating that indicating that the SLBP (show SLBP Proteins) degradation in G1 is independent of the previously identified SLBP (show SLBP Proteins) degradation at S/G2 (show STRN3 Proteins)

  5. Although the C-terminal tail of dSLBP (show SLBP Proteins) does not contact the RNA, phosphorylation of the tail promotes SLBP (show SLBP Proteins) conformations competent for RNA binding and thereby appears to reduce the entropic penalty for the association.

  6. correlation between the percentage of STAM2-positive cells and mitotic count was statistically significant in Gastrointestinal stromal tumors

  7. C-terminal extension of Lsm4 (show LSM4 Proteins) interacts directly with the histone mRNP, contacting both SLBP (show SLBP Proteins) and 3'hExo (show ERI1 Proteins).

  8. This paper describes the biophysical characterization of human SLBP (show SLBP Proteins) and the SLBP (show SLBP Proteins)-SLIP1 (show MIF4GD Proteins) complex. Human SLBP (show SLBP Proteins) is an intrinsically disordered protein that is phosphorylated at 23 Ser (show SIGLEC1 Proteins)/Thr (show TRH Proteins) sites when expressed in a eukaryotic expression system such as baculovirus. Unphosphorylated human SLBP (show SLBP Proteins) forms a high affinity heterotetramer with SLIP1 (show MIF4GD Proteins) and the SLBP (show SLBP Proteins)-SLIP1 (show MIF4GD Proteins) complex is regulated by SLBP (show SLBP Proteins) phosphorylation.

  9. Using yeast two-hybrid screening, the authors identify CT initiation factor-interacting protein (CTIF (show KIAA0427 Proteins)) as a protein that binds directly to SLBP (show SLBP Proteins). SLBP (show SLBP Proteins) preferentially associates with the CT complex of histone mRNAs consisting of CBP80 (show NCBP1 Proteins)/CBP20 (show NCBP2 Proteins), but not with the eIF4E (show EIF4E Proteins)/eIF4G (show EIF4G1 Proteins) (ET) complex, as has been proposed. Rapid degradation of histone mRNA on the inhibition of DNA replication requires association of SLBP (show SLBP Proteins) with CTIF (show KIAA0427 Proteins).

  10. This paper shows that SLBP (show SLBP Proteins) is a substrate for the prolyl isomerase Pin1 (show PIN1 Proteins). Pin1 (show PIN1 Proteins), along with PP2A (show PPP2R4 Proteins), facilitates dissociation of the SLBP (show SLBP Proteins)-histone mRNA complex at the end of S-phase, thereby promoting histone mRNA decay and SLBP (show SLBP Proteins) ubiquitination.

Mouse (Murine) Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 2 (STAM2) interaction partners

  1. Stam2 is expressed in the nervous tissue, heart, digestive and endocrine system during embryo development.

  2. These results demonstrate that the STAMs are indispensably involved in T-cell development and survival in the thymus through the prevention of apoptosis but are dispensable for the proximal signaling of TCR and cytokine receptors.

  3. STAM (show STAM Proteins) proteins function in a multivalent complex that sorts ubiquitinated proteins into the multivesicular body pathway.

  4. SH3 domains of STAM2 and Grb2 (show GRB2 Proteins) retain the moderate characteristics of recognizing their ligand proteins like other SH3 domains for signal protein (show KLK7 Proteins) binding

Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 2 (STAM2) Protein Profile

Protein Summary

This gene encodes a protein that binds to the stem-loop structure in replication-dependent histone mRNAs. Histone mRNAs do not contain introns or polyadenylation signals, and are processed by endonucleolytic cleavage. The stem-loop structure is essential for efficient processing but this structure also controls the transport, translation and stability of histone mRNAs. Expression of the protein is regulated during the cell cycle, increasing more than 10-fold during the latter part of G1.

Alternative names and synonyms associated with Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 2 (STAM2)

  • signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 (stam2)
  • signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 (STAM2)
  • signal transducing adapter molecule 2-like (STAM2)
  • signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 (LOC100222318)
  • signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 (Stam2)
  • stem-loop binding protein (SLBP)
  • 1200004O12Rik protein
  • 5730456G07Rik protein
  • BB145015 protein
  • HBP protein
  • MGC52950 protein
  • stam2 protein
  • STAM2A protein
  • STAM2B protein
  • zgc:103628 protein

Protein level used designations for STAM2

signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 , signal transducing adapter molecule 2 , signal transducing adaptor molecule 2 , signal transducing adapter molecule 2-like , HSE1 homolog , Hrs-binding protein , STAM-2 , STAM-like protein containing SH3 and ITAM domains 2 , Hrs binding protein , hrs-binding protein , EAST protein , epidermal growth factor receptor-associated protein with SH3 and TAM domain , hairpin binding protein, histone , histone RNA hairpin-binding protein , histone binding protein , histone stem-loop binding protein , histone stem-loop-binding protein , stem-loop (histone) binding protein

GENE ID SPECIES
380121 Xenopus laevis
459661 Pan troglodytes
492497 Danio rerio
538505 Bos taurus
695286 Macaca mulatta
100020075 Monodelphis domestica
100057966 Equus caballus
100222318 Taeniopygia guttata
100351322 Oryctolagus cuniculus
100389794 Callithrix jacchus
100490315 Xenopus (Silurana) tropicalis
100560924 Anolis carolinensis
100484799 Ailuropoda melanoleuca
10254 Homo sapiens
476150 Canis lupus familiaris
56324 Mus musculus
311030 Rattus norvegicus
424317 Gallus gallus
7884 Homo sapiens
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