MYZAP antibody (C-Term)
MYZAP
Reactivity: Human, Mouse, Rat
WB, ELISA, IHC (p), IF
Host: Rabbit
Polyclonal
unconjugated
-
- Target See all MYZAP Antibodies
- MYZAP (Myocardial Zonula Adherens Protein (MYZAP))
- Binding Specificity
- AA 400-450, C-Term
- Reactivity
- Human, Mouse, Rat
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This MYZAP antibody is un-conjugated
-
Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- Specificity
- Multiple isoforms of MYOZAP are known to exist.
- Purification
- MYOZAP Antibody is affinity chromatography purified via peptide column.
- Immunogen
- MYOZAP antibody was raised against a 18 amino acid synthetic peptide near the carboxy terminus of human MYOZAP. The immunogen is located within amino acids 400 - 450 of MYOZAP.
- Isotype
- IgG
-
anti-Myocardial Zonula Adherens Protein (MYZAP) (C-Term) antibody
MYZAP Reactivity: Human, Mouse, Rat WB, EIA Host: Rabbit Polyclonal unconjugated
-
- Application Notes
-
MYOZAP antibody can be used for detection of MYOZAP by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. - Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- MYOZAP Antibody is supplied in PBS containing 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,4 °C
- Storage Comment
- MYOZAP antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
-
- Target
- MYZAP (Myocardial Zonula Adherens Protein (MYZAP))
- Alternative Name
- MYOZAP (MYZAP Products)
- Synonyms
- AA407270 antibody, AV006038 antibody, Gcom1 antibody, Gm640 antibody, Grinl1a7 antibody, Myozap antibody, Myzap antibody, GLURR2 antibody, GRINL1B antibody, GCOM1 antibody, Gup antibody, Gup1 antibody, Gup2 antibody, MYOZAP antibody, myocardial zonula adherens protein antibody, GRINL1B complex locus 2 (pseudogene) antibody, Myzap antibody, GCOM2 antibody, MYZAP antibody
- Background
- MYOZAP Antibody: MYOZAP, also known as GRINL1A, is a 54 kDa highly conserved cardiac protein. It is strongly expressed in the heart and lung and is a novel component of intercalated disc. MYOZAP interacts with myosin phosphatase-RhoA interacting protein (MRIP) and acts as an activator of Rho-dependent SRF signaling. Knockdown study in zebrafish results in cardiomyopathy with severe dysfunction. The MYOZAP gene is part of a complex transcript unit that includes the gene for glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A (GRINL1A). Transcription of this gene occurs at an upstream promoter, with two different groups of alternatively spliced variants: Gup for GRINL1A upstream transcripts and Gcom for GRINL1A combined transcripts.
- Gene ID
- 100820829
- NCBI Accession
- NP_001018110
- UniProt
- P0CAP1
-
You are here:
