Deoxyuridine Triphosphatase (DUT) antibody
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- Target See all Deoxyuridine Triphosphatase (DUT) Antibodies
- Deoxyuridine Triphosphatase (DUT)
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Reactivity
- Human, Rat, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- Un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein of human DUT (NP_001020419.1).
- Isotype
- IgG
- Top Product
- Discover our top product DUT Primary Antibody
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anti-Deoxyuridine Triphosphatase (DUT) (AA 68-164) antibody
DUT Reactivity: Human WB, ELISA, IHC (p), IF Host: Mouse Monoclonal 1C9 unconjugated
anti-Deoxyuridine Triphosphatase (DUT) (AA 89-252) antibodyDUT Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Deoxyuridine Triphosphatase (DUT) (Internal Region) antibodyVerified DUT Reactivity: Human WB, IHC, ELISA Host: Goat Polyclonal unconjugated
anti-Deoxyuridine Triphosphatase (DUT) (AA 151-252) antibodyDUT Reactivity: Human, Mouse WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Deoxyuridine Triphosphatase (DUT) antibodyDUT Reactivity: Human, Rat WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-Deoxyuridine Triphosphatase (DUT) (AA 1-252) antibodyDUT Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated
anti-Deoxyuridine Triphosphatase (DUT) (C-Term) antibodyDUT Reactivity: Human, Rat, Mouse, Dog, Saccharomyces cerevisiae, Zebrafish (Danio rerio), Bat, Guinea Pig, Horse WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Deoxyuridine Triphosphatase (DUT) (C-Term) antibodyDUT Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Deoxyuridine Triphosphatase (DUT) (N-Term) antibodyDUT Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Deoxyuridine Triphosphatase (DUT) (AA 170-198), (C-Term) antibodyDUT Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB 1:500-1:1000 IHC 1:50-1:200 IF 1:100-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- Deoxyuridine Triphosphatase (DUT)
- Alternative Name
- DUT (DUT Products)
- Synonyms
- BcDNA:LD08534 antibody, CG4584 antibody, Dmel\\CG4584 antibody, LD08534 antibody, UTPase antibody, anon-SAGE:Wang-077 antibody, dUTPase antibody, Tb07.27E10.390 antibody, dutpase antibody, 5031412I06Rik antibody, 5133400F09Rik antibody, D2Bwg0749e antibody, Dutp antibody, PIP4 antibody, deoxyuridine triphosphatase antibody, Deoxyuridine triphosphatase antibody, dUTPase; ORF54; similar to EBV BLLF3, CMV UL72, HSV UL50 antibody, involved in nucleotide metabolism antibody, tegument protein antibody, dUTPase antibody, deoxyuridine triphosphatase L homeolog antibody, DUT antibody, dUTPase antibody, P18 antibody, AlHV1gp51 antibody, UL50 antibody, HVT058 antibody, ORF9 antibody, ORF8 antibody, U45 antibody, GAMMAHV.ORF54 antibody, Tc00.1047053509151.130 antibody, Tc00.1047053508175.160 antibody, Tb927.7.5160 antibody, dut.L antibody, Dut antibody
- Target Type
- Viral Protein
- Background
- This gene encodes an essential enzyme of nucleotide metabolism. The encoded protein forms a ubiquitous, homotetrameric enzyme that hydrolyzes dUTP to dUMP and pyrophosphate. This reaction serves two cellular purposes: providing a precursor (dUMP) for the synthesis of thymine nucleotides needed for DNA replication, and limiting intracellular pools of dUTP. Elevated levels of dUTP lead to increased incorporation of uracil into DNA, which induces extensive excision repair mediated by uracil glycosylase. This repair process, resulting in the removal and reincorporation of dUTP, is self-defeating and leads to DNA fragmentation and cell death. Alternative splicing of this gene leads to different isoforms that localize to either the mitochondrion or nucleus. A related pseudogene is located on chromosome 19.
- Molecular Weight
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Observed_MW: 24 kDa
Calculated_MW: 17 kDa/26 kDa
- Gene ID
- 1854
- UniProt
- P33316
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