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SSX2IP antibody (AA 485-614)

SSX2IP Reactivity: Human ELISA, WB, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7143574
  • Target See all SSX2IP Antibodies
    SSX2IP (Synovial Sarcoma, X Breakpoint 2 Interacting Protein (SSX2IP))
    Binding Specificity
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 485-614
    Reactivity
    • 25
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 20
    • 4
    • 1
    Rabbit
    Clonality
    • 23
    • 2
    Polyclonal
    Conjugate
    • 15
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SSX2IP antibody is un-conjugated
    Application
    • 13
    • 7
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Cross-Reactivity
    Human, Rat
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Afadin- and alpha-actinin-binding protein (485-614AA)
    Isotype
    IgG
  • Application Notes
    Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    SSX2IP (Synovial Sarcoma, X Breakpoint 2 Interacting Protein (SSX2IP))
    Alternative Name
    SSX2IP (SSX2IP Products)
    Synonyms
    zgc:73314 antibody, MGC83757 antibody, ADIP antibody, LCG antibody, AU014939 antibody, AU042321 antibody, Adip antibody, synovial sarcoma, X breakpoint 2 interacting protein a antibody, synovial sarcoma, X breakpoint 2 interacting protein S homeolog antibody, SSX family member 2 interacting protein antibody, synovial sarcoma, X 2 interacting protein antibody, ssx2ipa antibody, ssx2ip.S antibody, SSX2IP antibody, Ssx2ip antibody
    Background

    Background: Belongs to an adhesion system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). May connect the nectin-afadin and E-cadherin-catenin system through alpha-actinin and may be involved in organization of the actin cytoskeleton at AJs through afadin and alpha-actinin (By similarity). Involved in cell movement: localizes at the leading edge of moving cells in response to PDGF and is required for the formation of the leading edge and the promotion of cell movement, possibly via activation of Rac signaling (By similarity). Acts as a centrosome maturation factor, probably by maintaining the integrity of the pericentriolar material and proper microtubule nucleation at mitotic spindle poles. The function seems to implicate at least in part WRAP73, the SSX2IP:WRAP73 complex is proposed to act as regulator of spindle anchoring at the mitotic centrosome (PubMed:23816619, PubMed:26545777). Involved in ciliogenesis (PubMed:24356449). It is required for targeted recruitment of the BBSome, CEP290, RAB8, and SSTR3 to the cilia (PubMed:24356449).

    Aliases: ADIP antibody, ADIP_HUMAN antibody, Afadin and alpha actinin binding protein antibody, Afadin DIL domain interacting protein antibody, Afadin DIL domain-interacting protein antibody, Afadin- and alpha-actinin-binding protein antibody, FLJ10848 antibody, KIAA0923 antibody, MGC75026 antibody, OTTHUMP00000011574 antibody, SSX 2 interacting protein antibody, SSX2 interacting protein antibody, SSX2-interacting protein antibody, SSX2IP antibody, Synovial sarcoma X breakpoint 2 interacting protein antibody

    UniProt
    Q9Y2D8
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