CNGA3 antibody (AA 1-165)
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- Target See all CNGA3 Antibodies
- CNGA3 (Cyclic Nucleotide Gated Channel alpha 3 (CNGA3))
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Binding Specificity
- AA 1-165
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CNGA3 antibody is un-conjugated
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Application
- ELISA, Immunohistochemistry (IHC)
- Cross-Reactivity
- Human
- Purification
- Antigen Affinity Purified
- Immunogen
- Recombinant Human Cyclic nucleotide-gated cation channel alpha-3 protein (1-165AA)
- Isotype
- IgG
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anti-Cyclic Nucleotide Gated Channel alpha 3 (CNGA3) (N-Term) antibody
CNGA3 Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
anti-Cyclic Nucleotide Gated Channel alpha 3 (CNGA3) antibodyCNGA3 Reactivity: Human, Mouse WB, ELISA Host: Rabbit Polyclonal unconjugated
anti-Cyclic Nucleotide Gated Channel alpha 3 (CNGA3) (AA 1-165) antibodyCNGA3 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Cyclic Nucleotide Gated Channel alpha 3 (CNGA3) (AA 594-611), (C-Term), (Intracellular) antibodyCNGA3 Reactivity: Mouse, Rat WB, IHC, IF Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Recommended dilution: IHC:1:20-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- CNGA3 (Cyclic Nucleotide Gated Channel alpha 3 (CNGA3))
- Alternative Name
- CNGA3 (CNGA3 Products)
- Synonyms
- ACHM2 antibody, CCNC1 antibody, CCNCa antibody, CCNCalpha antibody, CNCG3 antibody, CNG3 antibody, CNGA3 antibody, cyclic nucleotide gated channel alpha 3 antibody, CNGA3 antibody, Cnga3 antibody
- Background
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Background: Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cyclic GMP which leads to an opening of the cation channel and thereby causing a depolarization of cone photoreceptors. Induced a flickering channel gating, weakened the outward rectification in the presence of extracellular calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficacy of the channel when coexpressed with CNGB3 (By similarity). Essential for the generation of light-evoked electrical responses in the red-, green- and blue sensitive cones.
Aliases: ACHM2 antibody, CCNC1 antibody, CCNCa antibody, CCNCalpha antibody, CNCG3 antibody, CNG 3 antibody, CNG channel alpha 3 antibody, CNG channel alpha-3 antibody, CNG-3 antibody, CNG3 antibody, CNGA3 antibody, Cnga3 cyclic nucleotide gated channel alpha 3 antibody, CNGA3_HUMAN antibody, Cone photoreceptor cGMP gated channel antibody, Cone photoreceptor cGMP gated channel alpha subunit antibody, Cone photoreceptor cGMP gated channel subunit alpha antibody, Cone photoreceptor cGMP-gated channel subunit alpha antibody, Cyclic nucleotide gated cation channel alpha 3 antibody, Cyclic nucleotide gated channel alpha 3 antibody, Cyclic nucleotide gated channel olfactory 3 antibody, Cyclic nucleotide gated channel rod photoreceptor subunit alpha antibody, Cyclic nucleotide-gated cation channel alpha-3 antibody, Cyclic nucleotide-gated channel alpha-3 antibody, OTTHUMP00000161120 antibody
- UniProt
- Q16281
- Pathways
- Phototransduction
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