TRPM6 antibody (AA 317-348)
(3 references)-
- Target See all TRPM6 Antibodies
- TRPM6 (Transient Receptor Potential Cation Channel, Subfamily M, Member 6 (TRPM6))
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Binding Specificity
- AA 317-348
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TRPM6 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This TRPM6 (CHAK2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 317-348 amino acids from the Central region of human TRPM6 (CHAK2).
- Clone
- RB3407
- Isotype
- Ig Fraction
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anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 6 (TRPM6) (AA 740-840) antibody
TRPM6 Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 6 (TRPM6) (AA 317-348) antibodyTRPM6 Reactivity: Human ELISA, IHC, WB Host: Rabbit Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 6 (TRPM6) (1st Extracellular Loop), (AA 802-815) antibodyTRPM6 Reactivity: Mouse, Rat IHC, WB Host: Rabbit Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 6 (TRPM6) antibodyTRPM6 Reactivity: Human ELISA, WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB: 1:1000. IHC-P: 1:10~50
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Expiry Date
- 6 months
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: "Up-Regulation of Transient Receptor Potential Melastatin 6 Channel Expression by Tumor Necrosis Factor-α in the Presence of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor." in: Journal of cellular physiology, Vol. 232, Issue 10, pp. 2841-2850, (2017) (PubMed).
: "Down-regulation of TRPM6-mediated magnesium influx by cyclosporin A." in: Naunyn-Schmiedeberg's archives of pharmacology, Vol. 377, Issue 4-6, pp. 333-43, (2008) (PubMed).
: "TRPM6 expression and cell proliferation are up-regulated by phosphorylation of ERK1/2 in renal epithelial cells." in: Biochemical and biophysical research communications, Vol. 369, Issue 4, pp. 1129-33, (2008) (PubMed).
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: "Up-Regulation of Transient Receptor Potential Melastatin 6 Channel Expression by Tumor Necrosis Factor-α in the Presence of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor." in: Journal of cellular physiology, Vol. 232, Issue 10, pp. 2841-2850, (2017) (PubMed).
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- Target
- TRPM6 (Transient Receptor Potential Cation Channel, Subfamily M, Member 6 (TRPM6))
- Alternative Name
- TRPM6 (CHAK2) (TRPM6 Products)
- Synonyms
- TRPM6 antibody, CHAK2 antibody, HMGX antibody, HOMG antibody, HOMG1 antibody, HSH antibody, TRPM6/CHAK2 antibody, transient receptor potential cation channel subfamily M member 6 antibody, transient receptor potential cation channel, subfamily M, member 6 antibody, TRPM6 antibody, Trpm6 antibody
- Background
- CHAK2 is a member of the ion channel proteins. It regulates the calcium concentration in cells, which is imperative for such functions as muscle contractions and neuronal firing. It is also upregulated in certain forms of cancer and could play a role in diabetes.
- Molecular Weight
- 231708
- Gene ID
- 140803
- NCBI Accession
- NP_001170781, NP_001170782, NP_060132
- UniProt
- Q9BX84
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