DDIT3 antibody (C-Term)
(3 references)-
- Target See all DDIT3 Antibodies
- DDIT3 (DNA-Damage-Inducible Transcript 3 (DDIT3))
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Binding Specificity
- C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This DDIT3 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF)
- Sequence
- GRTRKRKQSG HSPARAGKQR MKEKEQENER KVAQLAEENE RLKQEIERLT REVEATRRAL IDRMVNLHQA
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Polyclonal Antibodies
- Purification
- Affinity purification
- Immunogen
- A synthetic peptide corresponding to a sequence within amino acids 100 to the C-terminus of human DDIT3/CHOP (NP_004074.2).
- Isotype
- IgG
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anti-DNA-Damage-Inducible Transcript 3 (DDIT3) (AA 120-149), (C-Term) antibody
DDIT3 Reactivity: Human, Mouse WB, IF, FACS Host: Rabbit Polyclonal RB13788 unconjugated
anti-DNA-Damage-Inducible Transcript 3 (DDIT3) (AA 1-169) antibodyDDIT3 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-DNA-Damage-Inducible Transcript 3 (DDIT3) (N-Term) antibodyDDIT3 Reactivity: Human, Mouse WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-DNA-Damage-Inducible Transcript 3 (DDIT3) (N-Term) antibodyDDIT3 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-DNA-Damage-Inducible Transcript 3 (DDIT3) (pSer30) antibodyDDIT3 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-DNA-Damage-Inducible Transcript 3 (DDIT3) (AA 1-169) antibodyDDIT3 Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-DNA-Damage-Inducible Transcript 3 (DDIT3) (Ser301) antibodyDDIT3 Reactivity: Human, Mouse WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-DNA-Damage-Inducible Transcript 3 (DDIT3) antibodyDDIT3 Reactivity: Human, Mouse, Rat WB, IHC Host: Rabbit Polyclonal unconjugated
anti-DNA-Damage-Inducible Transcript 3 (DDIT3) antibodyDDIT3 Reactivity: Human WB, IHC Host: Rabbit Monoclonal unconjugated
anti-DNA-Damage-Inducible Transcript 3 (DDIT3) (AA 1-90) antibodyDDIT3 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 2G3 unconjugated
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- Application Notes
- WB,1:500 - 1:2000,IF,1:50 - 1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid freeze / thaw cycles
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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: "Autophagy May Protect Against Parenteral Nutrition-Associated Liver Disease by Suppressing Endoplasmic Reticulum Stress." in: JPEN. Journal of parenteral and enteral nutrition, Vol. 43, Issue 1, pp. 96-106, (2019) (PubMed).
: "Identification of ASB7 as ER stress responsive gene through a genome wide in silico screening for genes with ERSE." in: PLoS ONE, Vol. 13, Issue 4, pp. e0194310, (2018) (PubMed).
: "The TRiC chaperonin controls reovirus replication through outer-capsid folding." in: Nature microbiology, Vol. 3, Issue 4, pp. 481-493, (2018) (PubMed).
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: "Autophagy May Protect Against Parenteral Nutrition-Associated Liver Disease by Suppressing Endoplasmic Reticulum Stress." in: JPEN. Journal of parenteral and enteral nutrition, Vol. 43, Issue 1, pp. 96-106, (2019) (PubMed).
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- Target
- DDIT3 (DNA-Damage-Inducible Transcript 3 (DDIT3))
- Alternative Name
- DDIT3 (DDIT3 Products)
- Synonyms
- chop antibody, Xchop antibody, cebpz antibody, chop10 antibody, gadd153 antibody, CHOP-10 antibody, CHOP10 antibody, CHOP antibody, Chop10 antibody, Gadd153 antibody, CEBPZ antibody, GADD153 antibody, DNA damage inducible transcript 3 antibody, DNA-damage inducible transcript 3 antibody, DNA damage inducible transcript 3 L homeolog antibody, ddit3 antibody, Ddit3 antibody, DDIT3 antibody, ddit3.L antibody
- Background
- This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified.,DDIT3,CEBPZ,CHOP,CHOP-10,CHOP10,GADD153,C/EBPzeta,DDIT3 / CHOP,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,MAPK-P38 Signaling Pathway,Cell Biology & Developmental Biology,Autophagy,Protein folding,Endocrine & Metabolism,Endocrine and metabolic diseases,Diabetes,Metabolic disorders,Obesity,Stem Cells,Embryonic Stem Cells,DDIT3
- Molecular Weight
- 19 kDa/21 kDa
- Gene ID
- 1649
- UniProt
- P35638
- Pathways
- Regulation of Muscle Cell Differentiation, ER-Nucleus Signaling, Skeletal Muscle Fiber Development, Cell RedoxHomeostasis
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