NBL1 Protein (His tag)
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- Target See all NBL1 Proteins
- NBL1 (Neuroblastoma 1, DAN Family BMP Antagonist (NBL1))
- Protein Type
- Recombinant
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Origin
- Mouse
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Source
- Human Cells
- Purification tag / Conjugate
- This NBL1 protein is labelled with His tag.
- Purpose
- Recombinant Mouse NBL1/DAND1 Protein (His Tag)
- Sequence
- Ala17-Asp178
- Characteristics
- Recombinant Mouse Differential Screening-selected Gene Aberrant in Neuroblastoma is produced by our Mammalian expression system and the target gene encoding Ala17-Asp178 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by SDS-PAGE
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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Neuroblastoma 1, DAN Family BMP Antagonist (NBL1) (AA 17-181) protein (His-IF2DI Tag)
NBL1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Neuroblastoma 1, DAN Family BMP Antagonist (NBL1) (AA 1-180) protein (GST tag)NBL1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Neuroblastoma 1, DAN Family BMP Antagonist (NBL1) (AA 21-130) protein (GST tag)NBL1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Neuroblastoma 1, DAN Family BMP Antagonist (NBL1) (AA 17-181) protein (His tag)Crystallography grade NBL1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Neuroblastoma 1, DAN Family BMP Antagonist (NBL1) (AA 17-178) protein (His tag)Crystallography grade NBL1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- NBL1 (Neuroblastoma 1, DAN Family BMP Antagonist (NBL1))
- Alternative Name
- NBL1/DAND1 (NBL1 Products)
- Synonyms
- D1S1733E Protein, DAN Protein, DAND1 Protein, NB Protein, NO3 Protein, D4H1S1733E Protein, Dana Protein, dand1 Protein, nbl1-a Protein, no3 Protein, 4.1N Protein, Epb41l1 Protein, NBL1 Protein, mKIAA0338 Protein, C1orf151-NBL1 Protein, dan Protein, zgc:77251 Protein, neuroblastoma 1, DAN family BMP antagonist Protein, neuroblastoma, suppression of tumorigenicity 1 Protein, neuroblastoma 1, DAN family BMP antagonist L homeolog Protein, neuroblastoma suppressor of tumorigenicity 1 Protein, erythrocyte membrane protein band 4.1 like 1 Protein, MINOS1-NBL1 readthrough Protein, NBL1 Protein, Nbl1 Protein, nbl1.L Protein, LOC535280 Protein, Epb41l1 Protein, MINOS1-NBL1 Protein, nbl1 Protein
- Background
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Background: Differential screening-selected gene aberrative in neuroblastoma (DAN) is a member of the DAN family of secreted glycoproteins. DAN family antagonists are characterized by a DAN domain that contains a cystine knot motif which is essential for binding to BMP ligands. Members of this family include DAN, gremlin, protein related to DAN and cerberus (PRDC), cerberus, sclerostin (SOST) and uterine sensitization-associated gene 1 protein, and control diverse processes in growth, development and the cell cycle. It has also been reported that DAN family plays crucial role in early mouse embryo development by inhibiting the action of bone morphogenic proteins and modulating the action of transforming growth factor-β superfamily members. DAN is synthesized by small-to intermediate-sized DRG neurons and transported to the sensory nerve terminals in the skin or to the sensory nerve terminals in the dorsal horn. It has been reported that DAN is ubiquitously expressed in adult rat and human tissues. Morphological studies have revealed that, in adult rat, DAN mRNA is expressed ubiquitously in lung and brain, but not in liver.
Synonym: DAND1, NBL1, DAN domain family member 1, neuroblastoma suppressor of tumorigenicity 1, Protein N03, suppression of tumorigenicity 1,DAN,Dana
- Molecular Weight
- 18.4 kDa
- UniProt
- Q61477
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