PSMB4 antibody (Internal Region)
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- Target See all PSMB4 Antibodies
- PSMB4 (Proteasome (Prosome, Macropain) Subunit, beta Type, 4 (PSMB4))
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Binding Specificity
- Internal Region
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PSMB4 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Specificity
- PSMB4 Antibody detects endogenous levels of total PSMB4.
- Predicted Reactivity
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human PSMB4, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product PSMB4 Primary Antibody
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anti-Proteasome (Prosome, Macropain) Subunit, beta Type, 4 (PSMB4) (AA 46-264) antibody
PSMB4 Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) Subunit, beta Type, 4 (PSMB4) (AA 1-264) antibodyPSMB4 Reactivity: Human WB, ELISA, IHC (p) Host: Mouse Monoclonal 6G7-E8 unconjugated
anti-Proteasome (Prosome, Macropain) Subunit, beta Type, 4 (PSMB4) antibodyPSMB4 Reactivity: Human WB, IF, FACS Host: Mouse Monoclonal 5B5 unconjugated
anti-Proteasome (Prosome, Macropain) Subunit, beta Type, 4 (PSMB4) (Internal Region) antibodyVerified PSMB4 Reactivity: Human, Mouse WB, ELISA, IHC Host: Goat Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) Subunit, beta Type, 4 (PSMB4) antibodyPSMB4 Reactivity: Human, Mouse, Rat WB, IF Host: Rabbit Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) Subunit, beta Type, 4 (PSMB4) (AA 1-264) antibodyPSMB4 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) Subunit, beta Type, 4 (PSMB4) (AA 230-239) antibodyVerified PSMB4 Reactivity: Human, Mouse, Rat WB, ELISA Host: Goat Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) Subunit, beta Type, 4 (PSMB4) antibody (FITC)PSMB4 Reactivity: Human WB, ELISA, IHC, IHC (p) Host: Rabbit Polyclonal FITC
anti-Proteasome (Prosome, Macropain) Subunit, beta Type, 4 (PSMB4) antibody (HRP)PSMB4 Reactivity: Human WB, ELISA, IHC, IHC (p) Host: Rabbit Polyclonal HRP
anti-Proteasome (Prosome, Macropain) Subunit, beta Type, 4 (PSMB4) antibody (Biotin)PSMB4 Reactivity: Human WB, ELISA, IHC, IHC (p) Host: Rabbit Polyclonal Biotin
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- Application Notes
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- PSMB4 (Proteasome (Prosome, Macropain) Subunit, beta Type, 4 (PSMB4))
- Alternative Name
- PSMB4 (PSMB4 Products)
- Synonyms
- An18g06680 antibody, PSMB4 antibody, Pros-27 antibody, HN3 antibody, HsN3 antibody, PROS-26 antibody, PROS26 antibody, im:6909492 antibody, zgc:110330 antibody, proteasome subunit beta type-4 antibody, proteasome subunit beta 4 antibody, proteasome (prosome, macropain) subunit, beta type 4 antibody, proteasome subunit beta 4 L homeolog antibody, ANI_1_890164 antibody, PSMB4 antibody, psmb4 antibody, Psmb4 antibody, psmb4.L antibody
- Background
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Description: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1.
Gene: PSMB4
- Molecular Weight
- 29kDa
- Gene ID
- 5692
- UniProt
- P28070
- Pathways
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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