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RGS2 antibody (Internal Region)

RGS2 Reactivity: Human, Rat, Mouse ELISA, WB, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6264723
  • Target See all RGS2 Antibodies
    RGS2 (Regulator of G-Protein Signaling 2 (RGS2))
    Binding Specificity
    • 15
    • 14
    • 8
    • 8
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 56
    • 29
    • 15
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Rat, Mouse
    Host
    • 53
    • 3
    Rabbit
    Clonality
    • 55
    • 1
    Polyclonal
    Conjugate
    • 21
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This RGS2 antibody is un-conjugated
    Application
    • 30
    • 24
    • 13
    • 13
    • 6
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    RGS2 Antibody detects endogenous levels of total RGS2.
    Predicted Reactivity
    Pig,Bovine,Horse,Sheep,Rabbit,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human RGS2, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product RGS2 Primary Antibody
  • Application Notes
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    RGS2 (Regulator of G-Protein Signaling 2 (RGS2))
    Alternative Name
    RGS2 (RGS2 Products)
    Synonyms
    G0S8 antibody, GOS8 antibody, fa96c08 antibody, wu:fa96c08 antibody, wu:fj08f11 antibody, zgc:91965 antibody, g0s8 antibody, regulator of G protein signaling 2 antibody, regulator of G-protein signaling 2 antibody, regulator of G-protein signaling 2, 24kDa antibody, regulator of G-protein signaling 2 L homeolog antibody, RGS2 antibody, Rgs2 antibody, rgs2 antibody, rgs2.L antibody
    Background

    Description: Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (PubMed:11063746, PubMed:19478087). It is involved in the negative regulation of the angiotensin-activated signaling pathway (PubMed:28784619). Plays a role in the regulation of blood pressure in response to signaling via G protein-coupled receptors and GNAQ. Plays a role in regulating the constriction and relaxation of vascular smooth muscle (By similarity). Binds EIF2B5 and blocks its activity, thereby inhibiting the translation of mRNA into protein (PubMed:19736320).

    Gene: RGS2

    Molecular Weight
    24kDa
    Gene ID
    5997
    UniProt
    P41220
    Pathways
    Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Brown Fat Cell Differentiation
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