KCTD6 antibody (AA 1-237)
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- Target See all KCTD6 Antibodies
- KCTD6 (Potassium Channel Tetramerisation Domain Containing 6 (KCTD6))
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Binding Specificity
- AA 1-237
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This KCTD6 antibody is un-conjugated
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Application
- ELISA, Immunohistochemistry (IHC)
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human BTB/POZ domain-containing protein KCTD6 protein (1-237AA)
- Isotype
- IgG
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anti-Potassium Channel Tetramerisation Domain Containing 6 (KCTD6) (AA 32-70) antibody
KCTD6 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Potassium Channel Tetramerisation Domain Containing 6 (KCTD6) (N-Term) antibodyKCTD6 Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio) WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Potassium Channel Tetramerisation Domain Containing 6 (KCTD6) (AA 72-121) antibodyKCTD6 Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio), Bat, Chicken, Monkey, Pig WB Host: Rabbit Polyclonal unconjugated
anti-Potassium Channel Tetramerisation Domain Containing 6 (KCTD6) (AA 21-70) antibodyKCTD6 Reactivity: Human WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Potassium Channel Tetramerisation Domain Containing 6 (KCTD6) (AA 1-237) antibodyKCTD6 Reactivity: Human WB Host: Mouse Polyclonal unconjugated
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- Application Notes
- Recommended dilution: IHC:1:20-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- KCTD6 (Potassium Channel Tetramerisation Domain Containing 6 (KCTD6))
- Alternative Name
- KCTD6 (KCTD6 Products)
- Synonyms
- KCTD6 antibody, 5430433B02Rik antibody, AU044285 antibody, kctd6 antibody, zgc:91884 antibody, KCASH3 antibody, potassium channel tetramerization domain containing 6 antibody, potassium channel tetramerisation domain containing 6 antibody, potassium channel tetramerization domain containing 6b antibody, KCTD6 antibody, kctd6 antibody, Kctd6 antibody, kctd6b antibody
- Background
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Background: Probable substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex mediating the ubiquitination and subsequent proteasomal degradation of target proteins. Promotes the ubiquitination of HDAC1, the function seems to depend on KCTD11:KCTD6 oligomerization. Can function as antagonist of the Hedgehog pathway by affecting the nuclear transfer of transcription factor GLI1, the function probably occurs via HDAC1 down-regulation, keeping GLI1 acetylated and inactive. Inhibits cell growth and tumorigenicity of medulloblastoma (MDB) (PubMed:21472142). Involved in regulating protein levels of ANK1 isoform Mu17 probably implicating CUL3-dependent proteasomal degradation (PubMed:22573887).
Aliases: BTB/POZ domain-containing protein KCTD6 antibody, KCASH3 antibody, kctd6 antibody, KCTD6_HUMAN antibody, MGC27385 antibody, potassium channel tetramerization domain containing 6 antibody
- UniProt
- Q8NC69
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