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Metabotropic Glutamate Receptor 3 antibody (AA 433-576)

Name: Metabotropic Glutamate Receptor 3 antibody (AA 433-576)
Brand: antibodies-online
SKU: ABIN5611176
Price: 511.5 USD
Availability: InStock

GRM3 Reactivity: Human WB, ELISA, IHC, FACS, ICC, Neut Host: Mouse Monoclonal 6H10C3 unconjugated

Immunohistochemical analysis of paraffin-embedded bladder cancer tissues using GRM3 mouse mAb with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded stomach cancer tissues using GRM3 mouse mAb with DAB staining.

IHC

Black line: Control Antigen (100 ng),Purple line: Antigen (10 ng), Blue line: Antigen (50 ng), Red line:Antigen (100 ng)

ELISA

Western blot analysis using GRM3 mAb against HEK293 (1) and GRM3 (AA: extra 433-576)-hIgGFc transfected HEK293 (2) cell lysate.

Western blot analysis using GRM3 mAb against human GRM3 (AA: extra 433-576) recombinant protein.

Flow cytometric analysis of SH-SY5Y cells using GRM3 mouse mAb (green) and negative control (red).

FACS

6 images

Catalog No. ABIN5611176

Datasheet as PDF

Target See all Metabotropic Glutamate Receptor 3 (GRM3) Antibodies

Metabotropic Glutamate Receptor 3 (GRM3) (Glutamate Receptor, Metabotropic 3 (GRM3))
Binding Specificity
16

10

6

4

3

1

1

1

1

1

1

1

1

1

1

1
AA 433-576
Reactivity
40

31

14

11

7

6

4

4

4

3

2

2

2

2
Human
Host
55

1

1
Mouse
Compatible Secondaries
Clonality
55

2
Monoclonal
Conjugate
24

3

3

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1
This Metabotropic Glutamate Receptor 3 antibody is un-conjugated
Application
44

19

16

9

9

5

3

1

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC), Neutralization (Neut)

Purification

purified

Immunogen

Purified recombinant fragment of human GRM3 (AA: extra 433-576) expressed in E. coli.

Clone

6H10C3

Isotype

IgG1
anti-Glutamate Receptor, Metabotropic 3 (GRM3) (AA 433-576) antibody
GRM3 Reactivity: Human WB, ELISA, IHC, FACS, ICC Host: Mouse Monoclonal 7A5A6 unconjugated

anti-Glutamate Receptor, Metabotropic 3 (GRM3) (N-Term) antibody
GRM3 Reactivity: Human, Cow, Horse, Monkey, Pig WB, IHC, ICC, IHC (p) Host: Rabbit Polyclonal unconjugated

anti-Glutamate Receptor, Metabotropic 3 (GRM3) (N-Term) antibody
GRM3 Reactivity: Human, Mouse, Rat, Cow, Horse, Monkey, Pig, Hamster IHC, ICC, IHC (p) Host: Rabbit Polyclonal unconjugated

anti-Glutamate Receptor, Metabotropic 3 (GRM3) (C-Term) antibody
GRM3 Reactivity: Human, Mouse, Rat WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated

anti-Glutamate Receptor, Metabotropic 3 (GRM3) (C-Term) antibody
GRM3 Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated

anti-Glutamate Receptor, Metabotropic 3 (GRM3) (AA 23-170) antibody
GRM3 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated

anti-Glutamate Receptor, Metabotropic 3 (GRM3) (Extracellular Domain) antibody
GRM3 Reactivity: Human, Mouse, Rat, Cow, Horse, Monkey, Pig, Hamster, Orang-Utan, Gorilla ICC, IHC (p) Host: Rabbit Polyclonal unconjugated

anti-Glutamate Receptor, Metabotropic 3 (GRM3) (Extracellular Domain) antibody
GRM3 Reactivity: Human, Cow, Horse, Monkey, Pig, Orang-Utan, Gorilla WB, ICC, IHC (p) Host: Rabbit Polyclonal unconjugated

anti-Glutamate Receptor, Metabotropic 3 (GRM3) (AA 24-38), (Extracellular), (N-Term) antibody
GRM3 Reactivity: Mouse, Rat WB, IHC, ICC, IF, LCI Host: Rabbit Polyclonal unconjugated

anti-Glutamate Receptor, Metabotropic 3 (GRM3) (AA 46-354) antibody
GRM3 Reactivity: Human ELISA, IF Host: Rabbit Polyclonal unconjugated

Application Notes

ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: 1:200 - 1:400, IHC: 1:200 - 1:1000

Restrictions

For Research Use only
Format

Liquid

Buffer

Purified antibody in PBS with 0.05 % sodium azide

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

4 °C/-20 °C

Storage Comment

4°C, -20°C for long term storage
Target

Metabotropic Glutamate Receptor 3 (GRM3) (Glutamate Receptor, Metabotropic 3 (GRM3))

Alternative Name

GRM3 (GRM3 Products)

Synonyms

GLUR3 antibody, GPRC1C antibody, MGLUR3 antibody, mGlu3 antibody, 0710001G23Rik antibody, Gprc1c antibody, mGluR3 antibody, glutamate metabotropic receptor 3 antibody, glutamate receptor, metabotropic 3 antibody, GRM3 antibody, Grm3 antibody

Background

Description: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.
Aliases: GLUR3, mGlu3, GPRC1C, MGLUR3

Molecular Weight

99 kDa

Gene ID

2913

HGNC

2913

Pathways

cAMP Metabolic Process, Synaptic Membrane