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GSTM3 antibody (AA 93-206)

GSTM3 Reactivity: Human, Mouse, Rat WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5693252
  • Target See all GSTM3 Antibodies
    GSTM3 (Glutathione S-Transferase mu 3 (Brain) (GSTM3))
    Binding Specificity
    • 8
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 93-206
    Reactivity
    • 25
    • 11
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Human, Mouse, Rat
    Host
    • 19
    • 6
    • 2
    Rabbit
    Clonality
    • 23
    • 4
    Polyclonal
    Conjugate
    • 22
    • 2
    • 1
    • 1
    • 1
    This GSTM3 antibody is un-conjugated
    Application
    • 18
    • 10
    • 8
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Brand
    Picoband™
    Cross-Reactivity (Details)
    No cross reactivity with other proteins.
    Characteristics
    Rabbit IgG polyclonal antibody for GSTM3 detection. Tested with WB, IHC-P, Direct ELISA in Human,Mouse,Rat.
    Immunogen
    E. coli-derived human GSTM3 recombinant protein (Position: E93-Q206).
  • Application Notes

    Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).

    Application Details: Western blot, 0.1-0.5 μg/mL
    Immunohistochemistry(Paraffin-embedded Section), 0.5-1 μg/mL
    Direct ELISA, 0.1-0.5 μg/mL

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Buffer
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
  • Target
    GSTM3 (Glutathione S-Transferase mu 3 (Brain) (GSTM3))
    Alternative Name
    GSTM3 (GSTM3 Products)
    Synonyms
    GST5 antibody, GSTB antibody, GSTM3-3 antibody, GTM3 antibody, Fsc2 antibody, mGSTM5 antibody, glutathione S-transferase mu 3 antibody, glutathione S-transferase Mu 3 antibody, glutathione S-transferase, mu 3 antibody, GSTM3 antibody, Gstm3 antibody, LOC479911 antibody
    Background

    Synonyms: Glutathione S-transferase Mu 3, GST class-mu 3, GSTM3-3, hGSTM3-3, GSTM3, GST5,

    Tissue Specificity: Testis and brain.

    Background: Glutathione S-transferase M3 (brain), also known as GSTM3, is an enzyme which in humans is encoded by theGSTM3 gene. Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Mutations of this class mu gene have been linked with a slight increase in a number of cancers, likely due to exposure with environmental toxins.

    UniProt
    P21266
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